Population Pharmacokinetics and Exposure-Safety Relationships of Alisertib in Children and Adolescents With Advanced Malignancies

Zhou, XF; Mould, DR; Yuan, Y; Fox, E; Greengard, E; Faller, DV; Venkatakrishnan, K

Zhou, XF (通讯作者)，Millennium Pharmaceut Inc, Quantitat Clin Pharmacol, 40 Landsdowne St, Cambridge, MA 02139 USA.

JOURNAL OF CLINICAL PHARMACOLOGY, 2022; 62 (2): 206

Abstract

Population pharmacokinetic (PK) and exposure-safety analyses of alisertib were performed in children enrolled in 2 clinical trials: NCT02444884 and NC......

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