Inhibition of the all-trans Retinoic Acid (atRA) Hydroxylases CYP26A1 and CYP26B1 Results in Dynamic, Tissue-Specific Changes in Endogenous atRA Signaling

Stevison, F; Hogarth, C; Tripathy, S; Kent, T; Isoherranen, N

Isoherranen, N (reprint author), Univ Washington, Dept Pharmaceut, Sch Pharm, Hlth Sci Bldg Room H-272M,Box 357610, Seattle, WA 98195 USA.

DRUG METABOLISM AND DISPOSITION, 2017; 45 (7): 846

Abstract

All-trans retinoic acid (atRA), the active metabolite of vitamin A, is a ligand for several nuclear receptors and acts as a critical regulator of many......

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