PHYOX2: a pivotal randomized study of nedosiran in primary hyperoxaluria type 1 or 2

Baum, MA; Langman, C; Cochat, P; Lieske, JC; Moochhala, SH; Hamamoto, S; Satoh, H; Mourani, C; Ariceta, G; Torres, A; Wolley, M; Belostotsky, V; Forbes, TA; Groothoff, J; Hayes, W; Tönshoff, B; Takayama, T; Rosskamp, R; Russell, K; Zhou, J; Amrite, A; Hoppe, B

Hoppe, B (通讯作者),German Hyperoxaluria Ctr, Kindernierenzentrum, Muhlenbach 2b, D-53127 Bonn, Germany.

KIDNEY INTERNATIONAL, 2023; 103 (1): 207

Abstract

Nedosiran is an investigational RNA interference agent designed to inhibit expression of hepatic lactate dehydrogenase, the enzyme thought responsible......

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