JAMA Cardiol:Meta分析:高危患者服用ω-3脂肪酸对心血管无益

2018-02-05 xujing 中国循环杂志

近期,牛津大学学者在JAMA内科上发表的一项Meta分析表明,每日补充ω-3脂肪酸(FAS)并不能降低高危人群致命或非致命性冠心病或大血管事件的发生率。

近期,牛津大学学者在JAMA内科上发表的一项Meta分析表明,每日补充ω-3脂肪酸(FAS)并不能降低高危人群致命或非致命性冠心病或大血管事件的发生率。

研究人员发现,至少12个月的补充ω-3脂肪酸对冠心病事件的发生率无影响(RR=0.96),包括非致命性心肌梗死(RR=0.97)或冠心病死亡(RR=0.93)。

ω-3脂肪酸也未降低大血管事件(RR=0.97)、卒中(RR=1.03)或再灌注治疗(RR=0.99)的风险。

因此,研究者指出,该结果不支持当前的AHA指南的推荐即冠心病高危患者应服用ω-3脂肪酸以预防CVD。

在去年的一份AHA科学声明中,对于已患冠心病或射血分数降低心衰的患者,补充ω-3脂肪酸是合理的,但由于缺乏随机数据,没有推荐使用一级预防。相反,欧洲指南认为,ω-3脂肪酸是否有保护作用需要更多的证据来证明。

该分析了10个随机对照研究,纳入77 917名心血管疾病高危患者。

原始出处:Aung T, Halsey J, Kromhout D, et al. Associations of omega-3 fatty acidsupplement use with cardiovascular disease risks: meta-analysis of 10 trialsinvolving 77,917 individuals. JAMA Cardiol. Published online January31, 2018.

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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Mar 08 07:32:32 CST 2018, time=2018-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292611, encodeId=f06c292611f6, content=大家分享一下.很好的idea, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sat Mar 03 12:02:41 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896262, encodeId=3fd3189626245, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Mar 07 20:04:00 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1329882, encodeId=3d7213298829d, content=<a href='/topic/show?id=8f3a19290dd' target=_blank style='color:#2F92EE;'>#ω-3脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19290, encryptionId=8f3a19290dd, topicName=ω-3脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=232a2500033, createdName=1249859em38(暂无昵称), createdTime=Wed Feb 07 10:04:00 CST 2018, time=2018-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285428, encodeId=1258285428ea, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Mon Feb 05 20:23:42 CST 2018, time=2018-02-05, status=1, ipAttribution=)]
    2018-03-19 guojianrong
  5. 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  6. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3b2c1627329, createdName=owlhealth, createdTime=Thu Mar 08 07:32:32 CST 2018, time=2018-03-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292611, encodeId=f06c292611f6, content=大家分享一下.很好的idea, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sat Mar 03 12:02:41 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896262, encodeId=3fd3189626245, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Mar 07 20:04:00 CST 2018, time=2018-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1329882, encodeId=3d7213298829d, content=<a href='/topic/show?id=8f3a19290dd' target=_blank style='color:#2F92EE;'>#ω-3脂肪酸#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=19290, encryptionId=8f3a19290dd, topicName=ω-3脂肪酸)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=232a2500033, createdName=1249859em38(暂无昵称), createdTime=Wed Feb 07 10:04:00 CST 2018, time=2018-02-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=285428, encodeId=1258285428ea, content=学习一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Mon Feb 05 20:23:42 CST 2018, time=2018-02-05, status=1, ipAttribution=)]
    2018-03-08 owlhealth

    不错耶.学习了

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Mon Feb 05 20:23:42 CST 2018, time=2018-02-05, status=1, ipAttribution=)]
    2018-03-03 张新亮1853311252142e2fm

    大家分享一下.很好的idea

    0

  8. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Mon Feb 05 20:23:42 CST 2018, time=2018-02-05, status=1, ipAttribution=)]
    2018-03-07 一闲
  9. 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    2018-02-05 changjiu

    学习一下谢谢

    0

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