Clin Oral Invest:光动力疗法治疗原发性牙髓感染的临床和微生物疗效

2018-04-27 MedSci MedSci原创

试验评估了光动力治疗(PDT)对临床成功(根尖周愈合)和原发性牙髓感染的微生物群的作用。

试验评估了光动力治疗(PDT)对临床成功(根尖周愈合)和原发性牙髓感染的微生物群的作用。

实验纳入32例患有下颌磨牙根尖周炎(1颗牙齿/患者)的患者,随机分为两组:对照组(化学机械清创[CMD]; n = 16)和PDT(CMD + PDT; n = 16) )。所有牙齿在充填前先氢氧化钙根管封药7天。在3个月和6个月进行随访,拍X光片观察。用根尖周指数(PAI)评价根尖周愈合情况。术前获取样本,在根充前用棋盘格确定37个分类群的频率和水平。

结果发现,随着时间的推移,两组的PAI评分均显着降低,但在6个月时,PDT组的愈合评分显着优于对照组(p <0.05)。在开始时,所有样本中最普遍的是白色念珠菌(46.9%),肺炎双球菌(31.2%),普雷沃氏菌(28.2%),普雷沃氏菌(28.1%)和消化链球菌(25%)。两组中,大多数菌种随着时间的推移均减少,并且两组之间没有观察到所测菌种频率和水平的显着差异。在治疗后3个月,两组中白色念珠菌和肺炎双球菌频率均高。

结论:常规牙髓治疗±PDT均可以有效降低微生物负荷,导致根尖周愈合。而辅助性PDT在6个月后根尖周愈合更好。

原始出处:

Rachel Garcia de Miranda, et al. Clinical and microbiological effectiveness of photodynamic therapy on primary endodontic infections: a 6-month randomized clinical trial.Clinical Oral Investigations. 2018 May. doi:10.1007/s00784-017-2270-4

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    2018-08-25 heli0118
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    2018-04-30 txqjm

    谢谢了.学习

    0

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    2018-04-28 内科新手

    谢谢梅斯提供这么好的信息,学到很多

    0

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    2018-06-07 jxrzshh

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