Sci Rep:小剂量的胸部放射引起循环系统疾病的风险不可忽视

2017-03-15 MedSci MedSci原创

目前很多报道表明,大剂量的电离辐射可导致循环系统疾病。但是暴露于低剂量(<0.5Gy)射线的风险仍不清楚。

目前很多报道表明,大剂量的电离辐射可导致循环系统疾病。但是暴露于低剂量(<0.5Gy)射线的风险仍不清楚。

少量信息表明,暴露的风险与暴露的年龄、时间的长短、射线剂量与频率相关。

该研究者对加拿大及马萨诸塞州的77275名结核病患者多次使用x线进行诊断。研究人群年龄幅度大,接受照射的剂量大多<0.5Gy。

研究者对这些接受了小剂量射线照射的患者进行了循环系统疾病病死率的评估。

结果表明:小剂量的射线照射导致循环系统疾病(n = 10209; Gy
= 0.246;95%CI0.036,0.469;p = 0.021)和缺血性心脏病(n = 6410; Gy = 0.267;95%CI0.003,0.552;p = 0.048)的死亡率均有上升趋势。增加放射的间隔时间有助于减少循环系统疾病及缺血性心脏病的风险(p<0.005)。在整个剂量范围内,剂量变化趋势与循环疾病(p=0.014) 及缺血性心肌病(p=0.003)的死亡率相关,这可能考虑是剂量相关的致死因素。

这些结果进一步证实和扩展了早期先关的研究,并有力的证明了<0.5Gy的辐射为循环系统疾病死亡率的风险因素。但是,生活方式及医疗相关的风险因素仍不能被完全排除在外。


原始出处:

Tran V1, Zablotska LB2, Brenner AV1,et al.Radiation-associated circulatory disease mortality in a pooled analysis of 77,275 patients from the Massachusetts and Canadian tuberculosis fluoroscopy cohorts.Sci Rep. 2017 Mar 13;7:44147. doi: 10.1038/srep44147

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    2017-10-18 pyaili
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    2017-04-04 明心见性

    <0.5Gy的辐射为循环系统疾病死亡率的风险因素。

    0

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    2017-03-19 明心见性

    不良生活方式比辐射的因素更容易引起循环系统疾病

    0

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    2017-03-15 Chongyang Zhang

    签到学习了很多。

    0

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