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JACC：氯吡格雷可有效治疗非ST段抬高型心肌梗死

2014-06-11 坞霜降 丁香园

氯吡格雷ST段抬高型心肌梗死
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尽管临床试验结果显示在不稳定心绞痛（UA）或非ST段抬高型心肌梗死（NSTEMI）患者治疗药物中，氯吡格雷具有降低心血管疾病（CV）发病率及死亡率的效果，但是有必要进一步评估氯吡格雷在实际临床工作中的治疗效力。 因此，Matthew D. Solomon博士等人从临床实际出发评估了氯吡格雷的效力，其研究结果发表于Journal of the American College of Cardi

尽管临床试验结果显示在不稳定心绞痛（UA）或非ST段抬高型心肌梗死（NSTEMI）患者治疗药物中，氯吡格雷具有降低心血管疾病（CV）发病率及死亡率的效果，但是有必要进一步评估氯吡格雷在实际临床工作中的治疗效力。

因此，Matthew D. Solomon博士等人从临床实际出发评估了氯吡格雷的效力，其研究结果发表于Journal of the American College of Cardiology杂志。【原文下载】

该回顾性队列研究选取了北加州凯萨医疗机构的患者，条件为无冠脉疾病病史、无氯吡格雷服用史、于2003年至2008年间出现UA或NSTEMI，同时研究者依照CUER研究排除了有卒中病史或短暂性脑缺血病史的患者。

在2年的随访中，研究者采用倾向型匹配多变量Cox分析法评估了氯吡格雷治疗与全因死亡率、因心梗入院情况及死亡心梗复合事件之间的关系。

该研究入组患者例数16365。36%的患者在出院7天内嘱给予氯吡格雷治疗。8562例患者的倾向匹配分析结果显示使用氯吡格雷后的因死亡率及心梗复合事件发生率较低，但心梗发生率并未降低。



Kaplan-Meier Curves for All-Cause Mortality and Acute MI

另一方面，氯吡格雷与死亡心梗复合事件的显著相关性仅表现在NSTEMI患者，而UA患者无表现。

此次大型社区基础的患者研究结果显示，氯吡格雷与心梗及死亡的综合发生率降低相关，而且这种相关性在NSTEMI患者群体尤为明显。

原始出处：

Solomon MD1, Go AS2, Shilane D3, Boothroyd DB3, Leong TK4, Kazi DS5, Chang TI3, Hlatky MA3.Comparative Effectiveness of Clopidogrel in Medically Managed Patients With Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction.J Am Coll Cardiol. 2014 Jun 3;63(21):2249-57. doi: 10.1016/j.jacc.2014.02.586. Epub 2014 Apr 2.【原文下载】

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    2014-08-11 hbwxf

    #JACC#

    0

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    2015-03-10 hxj0117

    #非ST段抬高型心肌梗死#

    0

  3. 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    2015-05-13 heli0118

    #非ST段抬高型#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1853282, encodeId=7d751853282fb, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Mon Aug 11 21:16:00 CST 2014, time=2014-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1967249, encodeId=2df2196e249c7, content=<a href='/topic/show?id=0973992313a' target=_blank style='color:#2F92EE;'>#非ST段抬高型心肌梗死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99231, encryptionId=0973992313a, topicName=非ST段抬高型心肌梗死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ac59108, createdName=hxj0117, createdTime=Tue Mar 10 05:16:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2066041, encodeId=5d522066041e4, content=<a href='/topic/show?id=fec79922910' target=_blank style='color:#2F92EE;'>#非ST段抬高型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99229, encryptionId=fec79922910, topicName=非ST段抬高型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Wed May 13 14:16:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1819090, encodeId=ec0018190903f, content=<a href='/topic/show?id=de2d99226e2' target=_blank style='color:#2F92EE;'>#非ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99226, encryptionId=de2d99226e2, topicName=非ST段)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Thu Jun 12 10:16:00 CST 2014, time=2014-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926975, encodeId=6aa619269e570, content=<a href='/topic/show?id=be549922826' target=_blank style='color:#2F92EE;'>#非ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99228, encryptionId=be549922826, topicName=非ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ed3112, createdName=echonoir, createdTime=Fri Feb 06 00:16:00 CST 2015, time=2015-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324938, encodeId=fc16132493895, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1422998, encodeId=b52014229981d, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619388, encodeId=6a49161938858, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624321, encodeId=b91a162432151, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=)]
    2014-06-12 lxg951

    #非ST段#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1853282, encodeId=7d751853282fb, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Mon Aug 11 21:16:00 CST 2014, time=2014-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1967249, encodeId=2df2196e249c7, content=<a href='/topic/show?id=0973992313a' target=_blank style='color:#2F92EE;'>#非ST段抬高型心肌梗死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99231, encryptionId=0973992313a, topicName=非ST段抬高型心肌梗死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ac59108, createdName=hxj0117, createdTime=Tue Mar 10 05:16:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2066041, encodeId=5d522066041e4, content=<a href='/topic/show?id=fec79922910' target=_blank style='color:#2F92EE;'>#非ST段抬高型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99229, encryptionId=fec79922910, topicName=非ST段抬高型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Wed May 13 14:16:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1819090, encodeId=ec0018190903f, content=<a href='/topic/show?id=de2d99226e2' target=_blank style='color:#2F92EE;'>#非ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99226, encryptionId=de2d99226e2, topicName=非ST段)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Thu Jun 12 10:16:00 CST 2014, time=2014-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926975, encodeId=6aa619269e570, content=<a href='/topic/show?id=be549922826' target=_blank style='color:#2F92EE;'>#非ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99228, encryptionId=be549922826, topicName=非ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ed3112, createdName=echonoir, createdTime=Fri Feb 06 00:16:00 CST 2015, time=2015-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324938, encodeId=fc16132493895, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1422998, encodeId=b52014229981d, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619388, encodeId=6a49161938858, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624321, encodeId=b91a162432151, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=)]
    2015-02-06 echonoir

    #非ST段抬高#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1853282, encodeId=7d751853282fb, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Mon Aug 11 21:16:00 CST 2014, time=2014-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1967249, encodeId=2df2196e249c7, content=<a href='/topic/show?id=0973992313a' target=_blank style='color:#2F92EE;'>#非ST段抬高型心肌梗死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99231, encryptionId=0973992313a, topicName=非ST段抬高型心肌梗死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ac59108, createdName=hxj0117, createdTime=Tue Mar 10 05:16:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2066041, encodeId=5d522066041e4, content=<a href='/topic/show?id=fec79922910' target=_blank style='color:#2F92EE;'>#非ST段抬高型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99229, encryptionId=fec79922910, topicName=非ST段抬高型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Wed May 13 14:16:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1819090, encodeId=ec0018190903f, content=<a href='/topic/show?id=de2d99226e2' target=_blank style='color:#2F92EE;'>#非ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99226, encryptionId=de2d99226e2, topicName=非ST段)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Thu Jun 12 10:16:00 CST 2014, time=2014-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926975, encodeId=6aa619269e570, content=<a href='/topic/show?id=be549922826' target=_blank style='color:#2F92EE;'>#非ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99228, encryptionId=be549922826, topicName=非ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ed3112, createdName=echonoir, createdTime=Fri Feb 06 00:16:00 CST 2015, time=2015-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324938, encodeId=fc16132493895, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1422998, encodeId=b52014229981d, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619388, encodeId=6a49161938858, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624321, encodeId=b91a162432151, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=)]
    2014-06-13 12498568m50暂无昵称

    #ACC#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1853282, encodeId=7d751853282fb, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Mon Aug 11 21:16:00 CST 2014, time=2014-08-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1967249, encodeId=2df2196e249c7, content=<a href='/topic/show?id=0973992313a' target=_blank style='color:#2F92EE;'>#非ST段抬高型心肌梗死#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99231, encryptionId=0973992313a, topicName=非ST段抬高型心肌梗死)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ac59108, createdName=hxj0117, createdTime=Tue Mar 10 05:16:00 CST 2015, time=2015-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2066041, encodeId=5d522066041e4, content=<a href='/topic/show?id=fec79922910' target=_blank style='color:#2F92EE;'>#非ST段抬高型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99229, encryptionId=fec79922910, topicName=非ST段抬高型)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=21015, createdName=heli0118, createdTime=Wed May 13 14:16:00 CST 2015, time=2015-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1819090, encodeId=ec0018190903f, content=<a href='/topic/show?id=de2d99226e2' target=_blank style='color:#2F92EE;'>#非ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99226, encryptionId=de2d99226e2, topicName=非ST段)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Thu Jun 12 10:16:00 CST 2014, time=2014-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1926975, encodeId=6aa619269e570, content=<a href='/topic/show?id=be549922826' target=_blank style='color:#2F92EE;'>#非ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99228, encryptionId=be549922826, topicName=非ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=5ed3112, createdName=echonoir, createdTime=Fri Feb 06 00:16:00 CST 2015, time=2015-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1324938, encodeId=fc16132493895, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1422998, encodeId=b52014229981d, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1619388, encodeId=6a49161938858, content=<a href='/topic/show?id=8dd46061824' target=_blank style='color:#2F92EE;'>#有效治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60618, encryptionId=8dd46061824, topicName=有效治疗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624321, encodeId=b91a162432151, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Fri Jun 13 05:16:00 CST 2014, time=2014-06-13, status=1, ipAttribution=)]
    2014-06-13 gdsun

    #ST段抬高#

    0

  8. 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    2014-06-13 docwu2019

    #有效治疗#

    0

  9. 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    2014-06-13 hyf035

    #ST段#

    0

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