PLOS ONE:什么影响ICU患者的一年死亡率:回顾性队列研究

2018-05-13 海北 MedSci原创

最近,来自MIT的研究人员试图确定在入住ICU后至少存活了30天的患者中,哪些因素与一年死亡率相关。

至今为止,我们对与从危重疾病康复后的一年死亡率相关的因素尚不清楚。临床医生通常缺乏关于重症监护病房患者出院后的信息,这在咨询患者和家属时可能很重要。最近,来自MIT的研究人员试图确定在入住ICU后至少存活了30天的患者中,哪些因素与一年死亡率相关。
这是一个单中心,纵向回顾性队列研究,所有ICU患者于2001 - 2012年入住三级医疗学术医疗中心,入住ICU后≥30天存活。研究人员使用Cox的比例风险模型来确定与一年死亡率相关的变量。主要结果是一年死亡率。
共有32,420名患者符合纳入标准并被纳入研究。在存活≥30天的患者中,28,583名(88.2%)存活超过1年,而3,837名(11.8%)没有。与一年生存率下降相关的变量包括:年龄增加,恶性肿瘤,上一年内住院次数,机械通气和血管活性药物使用的持续时间,败血症,充血性心力衰竭病史,终末期肾病,肝硬化,慢性阻塞性肺部疾病,以及需要进行肾脏替代治疗。
在重大疾病的幸存者中,有相当一部分人存活不到一年。需要更多的研究来帮助临床医生确定,哪些患者在急性病中存活之后,更可能在1年中死亡,从而改善影响这一结果的决策和护理的质量。

原始出处:
Lokhandwala S et al. One-year mortality after recovery from critical illness: A retrospective cohort study. PLOS ONE, 2018; DOI: 10.1371/journal.pone.0197226

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    2018-05-20 张新亮1853311252142e2fm

    好文献学习了

    0

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    2018-05-15 724765917_36481625

    学习了

    0

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  5. 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createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun May 13 09:03:03 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314687, encodeId=90b531468e47, content=ICU就是一个危险性高的患者, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sun May 13 08:47:26 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314677, encodeId=904b3146e79d, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun May 13 08:36:36 CST 2018, time=2018-05-13, status=1, ipAttribution=)]
    2018-05-13 131****1460

    学习了受益匪浅

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1790191, encodeId=e3bf1e90191ab, content=<a href='/topic/show?id=6e4814388e2' target=_blank style='color:#2F92EE;'>#Plos one#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14388, encryptionId=6e4814388e2, topicName=Plos one)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fda6311, createdName=119337457, createdTime=Tue Jan 22 13:53:00 CST 2019, time=2019-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=316816, encodeId=a00431681642, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Sun May 20 07:00:52 CST 2018, time=2018-05-20, status=1, ipAttribution=), 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Sun May 13 09:29:57 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314706, encodeId=24d7314e0627, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun May 13 09:25:50 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314697, encodeId=00b531469ef0, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Nd44v3xHnnictn9UpctwtH62EPQ59TMdI9lnqHMgQ16nH7GmGCfpzicsHgjibYVk6vwSpXrC86gMibRkoaIzf5HwSz7/0, createdBy=78cc1691107, createdName=龙胆草, createdTime=Sun May 13 09:03:03 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314687, encodeId=90b531468e47, content=ICU就是一个危险性高的患者, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160718/IMG578C993D395567540.jpg, createdBy=59b81918946, createdName=flysky120, createdTime=Sun May 13 08:47:26 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314677, encodeId=904b3146e79d, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun May 13 08:36:36 CST 2018, time=2018-05-13, status=1, ipAttribution=)]
    2018-05-13 baihao215

    单中心可以啊.牛X

    0

  7. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun May 13 08:36:36 CST 2018, time=2018-05-13, status=1, ipAttribution=)]
    2018-05-13 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLCclExeQ6LOGMD4dTsia4Ty4HtZCxRmG5vO5XIKfKX3a3vusfhHSej4Iib517vmhFW7RQgh7bpDp1yw/0, createdBy=50951609779, createdName=baihao215, createdTime=Sun May 13 09:29:57 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314706, encodeId=24d7314e0627, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Sun May 13 09:25:50 CST 2018, time=2018-05-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=314697, encodeId=00b531469ef0, content=学习谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun May 13 08:36:36 CST 2018, time=2018-05-13, status=1, ipAttribution=)]
    2018-05-13 龙胆草

    学习谢谢分享

    0

  9. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun May 13 08:36:36 CST 2018, time=2018-05-13, status=1, ipAttribution=)]
    2018-05-13 flysky120

    ICU就是一个危险性高的患者

    0

  10. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sun May 13 08:36:36 CST 2018, time=2018-05-13, status=1, ipAttribution=)]
    2018-05-13 明月清辉

    谢谢分享.学习了

    0

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