BMC Pregnancy Childbirth:儿童肥胖可能与母亲孕期行为有关

2015-05-10 MedSci MedSci原创

超重/肥胖是一种由多种因素引起的慢性代谢性疾病状态,表现为体内脂肪细胞的体积和数量的增加,导致体脂占体重的百分比异常增高,并可以在某些局部过多沉积脂肪。没有多少人想成为“白花花”的胖子,除了自己的不健康饮食、不喜爱运动等,母亲孕期的某些行为或许也该为后代的超重/肥胖负责。关于该问题,Mourtakos SP近期进行了一项研究,从国家数据库中随机提取5,125名孩子,并匹配其母亲,以探究妊娠期母亲体

超重/肥胖是一种由多种因素引起的慢性代谢性疾病状态,表现为体内脂肪细胞的体积和数量的增加,导致体脂占体重的百分比异常增高,并可以在某些局部过多沉积脂肪。没有多少人想成为“白花花”的胖子,除了自己的不健康饮食、不喜爱运动等,母亲孕期的某些行为或许也该为后代的超重/肥胖负责。

关于该问题,Mourtakos SP近期进行了一项研究,从国家数据库中随机提取5,125名孩子,并匹配其母亲,以探究妊娠期母亲体重增加、母亲妊娠年龄以及妊娠期母亲的生活方式(如:体力活动、吸烟和饮酒)是否会影响后代8岁时BMI。其研究结果发表在最近《BMC Pregnancy Childbirth》上。

研究者通过对参与者进行标准化问卷调查、电话随访收集相关信息,如母亲妊娠时年龄、孕期体重增加情况(GWG)、体育锻炼情况、是否吸烟喝酒等。研究者根据国家数据库对纳入的5,125名孩子计算了其8岁时BMI值。

研究结果显示,于孕期久坐不动相比较,孕期体重每增加1 kg,后代8岁时超重/肥胖的几率为1.01 (95%CI: 1.00, 1.02),若孕妇吸烟则该值为1.23 (95%CI: 1.03, 1.47),但是如果孕妇有适度的运动,则该数据显得相当乐观,仅为0.77 (95%CI: 0.65, 0.91)。进一步分析显示,对于孕期体重增长超出了医学研究所(IOM)要求的标准范围的女性,较之孕期GWG控制在适度范围内孕妇的后代相比,其后代8岁时超重/肥胖的风险显著增加(OR: 1.45; 95%CI, 1.26, 1.67)。目前的研究数据结果并没有发现母亲孕龄以及饮酒等因素与后代超重/肥胖有显著联系(p > 0.05)。

研究结果表明,母亲孕期体重增长情况、运动情况以及吸烟会对后代8岁时超重/肥胖的发生产生显著影响。根据研究结果,医疗保健人员应建议孕妇戒烟、适度运动等以减少后代超重/肥胖风险。

原始出处:

Mourtakos SP, Tambalis KD, Panagiotakos DB, et al. Maternal lifestyle characteristics during pregnancy, and the risk of obesity in the offspring: a study of 5,125 children. BMC Pregnancy Childbirth. 2015. 15: 66.

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    2015-09-06 docwu2019
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    2015-05-13 huaxipanxing

    看看

    0

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