Diabetologia:代谢综合征严重程度评分与未来糖尿病之间相关性

2017-06-21 MedSci MedSci原创

近日,国际杂志 《Diabetologia》上在线发表一项关于代谢综合征严重程度评分与未来糖尿病之间相关性的研究。旨在该研究旨在评估代谢综合征的严重程度与2型糖尿病风险之间的关系,除由代谢综合征的各个组分所导致的风险。

近日,国际杂志 《Diabetologia》上在线发表一项关于代谢综合征严重程度评分与未来糖尿病之间相关性的研究。旨在该研究旨在评估代谢综合征的严重程度与2型糖尿病风险之间的关系。 研究人员对随访时间中位数超过7.8年的两个观察队列(社区动脉粥样硬化风险研究(n = 10,957)和杰克逊心脏研究(n = 2137))中的参与者进行研究,并评估了成人治疗组III(ATP-III)的代谢综合征评分(ATP-III MetS)的HR值,以及与糖尿病相关的性别和种族特异性连续代谢综合征严重程度z评分。 ATP-III MetS糖尿病的HR为4.36(95%CI 3.83,4.97),其在包括个体代谢综合征成分的模型中有所减弱。相比之下,第四类代谢综合征严重程度(与第一类相比)的参与者未来糖尿病的HR为17.4(95%CI 12.6,24.1); 在还包括个体代谢综合征成分的模型中,这仍然是很重要的,该模型中HR为3.69(95%CI 2.42,5.64)。在这些模型中有一个种族×代谢综合征相互作用,黑人参与者(5.30)的HR比白人(2.24)更高。 当代谢综合征严重程度评分的变化包括在危险

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