Diabetes Care:髋部骨折后应激性高血糖增加急性心肌梗塞(AMI)风险

2013-07-24 Diabetes Care dxy

骨折与FBG的关系 为了研究髋部骨折后应激性高血糖之后的急性心肌梗塞(AMI)风险。来自北京首都医科大学北京安贞医院心内科的孟康教授及其团队进行了一项研究,研究发现,髋部骨折后应激性高血糖增加AMI风险。研究结果在线发表于2013年7月11日的美国《糖尿病治疗》(Diabetes Care)杂志上。 从2007年2月到2012年2月,研究人员对1,257名无糖尿病病史的


骨折与FBG的关系

为了研究髋部骨折后应激性高血糖之后的急性心肌梗塞(AMI)风险。来自北京首都医科大学北京安贞医院心内科的孟康教授及其团队进行了一项研究,研究发现,髋部骨折后应激性高血糖增加AMI风险。研究结果在线发表于2013年7月11日的美国《糖尿病治疗》(Diabetes Care)杂志上。

从2007年2月到2012年2月,研究人员对1,257名无糖尿病病史的连续髋部骨折患者进行了一项前瞻性观察分析。入院后对患者进行空腹血糖(FBG)和糖化血红蛋白试验以及心电图、超声心动图和胸部X线检查。根据FBG,将所有入选的髋部骨折患者分为应激性高血糖和非高血糖组,并监测AMI发生率。

结果显示,在参与试验的患者中,应激性高血糖的发生频率为47.89%,AMI为9.31%,应激性高血糖组AMI发生频率比非高血糖组高(P<0.05)。在应激性高血糖患者中,髋部骨折后2-3天,FBG水平达到最大值,然后逐渐降低。髋部骨折后最初3天,应激性高血糖组AMI发生率最高,为62.67%,与FBG达峰时间相吻合(P<0.05)。在所有AMI患者中,非ST段抬高心肌梗塞出现的频率较ST段抬高心肌梗塞高,分别为62.39%和37.61%。

研究发现,髋部骨折后应激性高血糖增加AMI风险。


Chen Y, Yang X, Meng K, Zeng Z, Ma B, Liu X, Qi B, Cui S, Cao P, Yang Y Stress-Induced Hyperglycemia After Hip Fracture and the Increased Risk of Acute Myocardial Infarction in Nondiabetic Patients Diabetes Care. 2013 Jul 11. 

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    2013-07-26 hbwxf
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    2013-07-26 liuquan
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