Physiol Genomics：什么？肠道菌群不健康也会让人患上高血压

2017-02-04 生物谷生物谷

日前，一项刊登在国际杂志Physiological Genomics上的题为“Alterations in the gut microbiota can elicit hypertension in rats”的研究报告中，来自休斯顿大学的研究人员通过对大鼠进行研究发现，大鼠肠道中寄居的

图片来源：www.sciencedaily.com

日前，一项刊登在国际杂志Physiological Genomics上的题为“Alterations in the gut microbiota can elicit hypertension in rats”的研究报告中，来自休斯顿大学的研究人员通过对大鼠进行研究发现，大鼠肠道中寄居的微生物群落或许在其患高血压上扮演着重要角色。

文章中，研究者对两组大鼠进行研究，其中一组大鼠患有高血压，另外一组大鼠血压正常，随后研究人员从每组大鼠的大肠中移除了一部分生物组织，随后给予每组大鼠为期10天的抗生素来减少其机体中天然微生物群落的水平，抗生素服用过后，研究者将高血压大鼠体内的微生物群落转移到正常血压的大鼠机体中，同时将正常大鼠体内的微生物群落转移到高血压大鼠机体中。

研究者发现，接受来自高血压大鼠机体微生物群落的大鼠的血压开始升高了，更有意思的是，利用正常大鼠体内微生物群落治疗的高血压大鼠的血压则并不会发生明显下降，尽管研究结果出现了略微下降。

这项研究为后期研究人员进行更为深入的研究奠定了基础，后期研究者还将深入研究是否这种情况也会在人类机体中出现，研究人员将对微生物群落引发人类高血压上进行研究，同时也为阐明益生菌是否能够作为治疗高血压的新型疗法提供了一定线索。本文研究结果表明，在饮食中补充益生菌对人类高血压有适度的有益影响，尤其是在高血压模型中表现尤为明显。

原始出处：

Adnan S, Nelson JW, Ajami NJ, Venna VR, Petrosino JF, Bryan RM Jr, Durgan DJ. Alterations in the gut microbiota can elicit hypertension in rats. Physiol Genomics. 2016 Dec 23:physiolgenomics.00081.2016.

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2017-08-01 cmj8wellington

#Physio#

30 0
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2017-11-13 luckyshitiancai_42705684

#genomics#

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2017-02-10 1e1f5604m96(暂无匿称)

可是只是动物研究啊

47 0
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2017-02-07 卡圣

长见识了

53 0
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2017-02-06 studylzc

看来得吃点益生菌了！

50 0
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2017-02-06 cqykthl

新进展，值得学习

56 0
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createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Sat Feb 04 21:04:00 CST 2017, time=2017-02-04, status=1, ipAttribution=)]
2017-02-06 1e1f732cm83(暂无匿称)

很新的观点，平时不怎么注意

46 0
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2017-02-05 1249897bm37(暂无昵称)

#肠道菌#

27 0
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2017-02-05 ylzr123

在饮食中补充益生菌对人类高血压有适度的有益影响，尤其是在高血压模型中表现尤为明显。

26 0
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2017-02-04 虈亣靌

很好，不错，以后会多学习

27 0