JCLA：应用药物洗脱支架经皮冠状动脉介入治疗冠心病患者快速血管造影狭窄进展和再狭窄风险的预测因素的综合分析

2019-06-03 不详网络

本研究旨在探讨经皮冠状动脉介入治疗(PCI)合并药物洗脱支架植入术后冠状动脉疾病(CAD)患者发生快速血管造影狭窄进展(RASP)和再狭窄的风险与基线、程序和术后特点的相关性。本研究连续登记接受PCI治疗并植入药物洗脱支架214例冠心病患者。收集患者的基线、程序和术后特征进行分析。冠状动脉造影评估PCI术前和PCI术后12个月的冠状动脉狭窄情况。然后评估非靶病变的RASP和支架植入靶病变的

本研究旨在探讨经皮冠状动脉介入治疗(PCI)合并药物洗脱支架植入术后冠状动脉疾病(CAD)患者发生快速血管造影狭窄进展(RASP)和再狭窄的风险与基线、程序和术后特点的相关性。

本研究连续登记接受PCI治疗并植入药物洗脱支架214例冠心病患者。收集患者的基线、程序和术后特征进行分析。冠状动脉造影评估PCI术前和PCI术后12个月的冠状动脉狭窄情况。然后评估非靶病变的RASP和支架植入靶病变的再狭窄。

37.8% CAD患者发PCI后12个月出现了RASP。RASP组出现糖尿病(DM)并发症增加、血清尿酸浓度较高(SUA)、心肌肌钙蛋白I N高终端probrain利钠肽和高灵敏度C反应蛋白以及多支冠状动脉病变的发生。此外，糖尿病、SUA、hs‐CRP和多血管病变单独可预测高RASP风险。对于再狭窄，21.0%的患者在PCI术后12个月发生再狭窄，再狭窄组患者出现高血压和糖尿病的发生率增加，SUA、LDL‐C和hs‐CRP浓度升高，与非再狭窄组相比，手术中靶病变和支架长度更长。此外，糖尿病、SUA、LDL‐C、hs‐CRP和靶病长度可独立预测再狭窄风险增加。

研究表明，糖尿病、SUA和hs‐CRP是冠心病患者行PCI和药物洗脱支架植入后RASP和再狭窄风险增加的潜在预测因素。

原始出处：

Yanqiang Wu, Xianghua Fu, Comprehensive analysis of predictive factors for rapid angiographic stenotic progression and restenosis risk in coronary artery disease patients underwent percutaneous coronary intervention with drug‐eluting stents implantation

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2019-06-15 zhixianchen

#洗脱支架#

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2019-06-12 3631181

#冠状动脉介入治疗#

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2019-08-30 sunlong28

学习~~~~~

54 0
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attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Aug 25 12:28:47 CST 2019, time=2019-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371722, encodeId=79be3e1722b4, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sat Aug 24 02:26:39 CST 2019, time=2019-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371677, encodeId=f6c83e167751, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Fri Aug 23 01:46:40 CST 2019, time=2019-08-23, status=1, ipAttribution=)]
2019-08-29 sunlong28

学习~~~~

39 0
[GetPortalCommentsPageByObjectIdResponse(id=1998773, encodeId=35371998e7349, content=<a href='/topic/show?id=80936510423' target=_blank style='color:#2F92EE;'>#洗脱支架#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65104, encryptionId=80936510423, topicName=洗脱支架)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Sat Jun 15 07:49:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1648949, encodeId=ccc21648949ab, content=<a href='/topic/show?id=6e0630843d0' target=_blank style='color:#2F92EE;'>#冠状动脉介入治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30843, encryptionId=6e0630843d0, topicName=冠状动脉介入治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Fri Aug 23 01:46:40 CST 2019, time=2019-08-23, status=1, ipAttribution=)]
2019-08-28 sunlong28

学习~~~~

50 0
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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Fri Aug 23 01:46:40 CST 2019, time=2019-08-23, status=1, ipAttribution=)]
2019-08-27 sunlong28

学习~~~~

40 0
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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Fri Aug 23 01:46:40 CST 2019, time=2019-08-23, status=1, ipAttribution=)]
2019-08-26 sunlong28

学习~~~~

57 0
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attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Aug 25 12:28:47 CST 2019, time=2019-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371722, encodeId=79be3e1722b4, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sat Aug 24 02:26:39 CST 2019, time=2019-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371677, encodeId=f6c83e167751, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Fri Aug 23 01:46:40 CST 2019, time=2019-08-23, status=1, ipAttribution=)]
2019-08-25 sunlong28

学习~~~~

21 0
[GetPortalCommentsPageByObjectIdResponse(id=1998773, encodeId=35371998e7349, content=<a href='/topic/show?id=80936510423' target=_blank style='color:#2F92EE;'>#洗脱支架#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65104, encryptionId=80936510423, topicName=洗脱支架)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Sat Jun 15 07:49:00 CST 2019, time=2019-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1648949, encodeId=ccc21648949ab, content=<a href='/topic/show?id=6e0630843d0' target=_blank style='color:#2F92EE;'>#冠状动脉介入治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30843, encryptionId=6e0630843d0, topicName=冠状动脉介入治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, 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authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Aug 27 06:15:16 CST 2019, time=2019-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371809, encodeId=13823e18093d, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Mon Aug 26 06:50:35 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371781, encodeId=56583e1781d4, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Aug 25 12:28:47 CST 2019, time=2019-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371722, encodeId=79be3e1722b4, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sat Aug 24 02:26:39 CST 2019, time=2019-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371677, encodeId=f6c83e167751, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Fri Aug 23 01:46:40 CST 2019, time=2019-08-23, status=1, ipAttribution=)]
2019-08-24 sunlong28

学习~~~~

25 0
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authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Tue Aug 27 06:15:16 CST 2019, time=2019-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371809, encodeId=13823e18093d, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Mon Aug 26 06:50:35 CST 2019, time=2019-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371781, encodeId=56583e1781d4, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sun Aug 25 12:28:47 CST 2019, time=2019-08-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371722, encodeId=79be3e1722b4, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Sat Aug 24 02:26:39 CST 2019, time=2019-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371677, encodeId=f6c83e167751, content=学习~~~~, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/05/26/5e1df344d663496bdfd43c465d409e2c.jpg, createdBy=bce679058, createdName=sunlong28, createdTime=Fri Aug 23 01:46:40 CST 2019, time=2019-08-23, status=1, ipAttribution=)]
2019-08-23 sunlong28

学习~~~~

26 0

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