Int J Cardiol:心源性猝死患者亲属的临床管理结局!

2018-03-09 xing.T MedSci原创

由此可见,当采用基于指南的评估和护理时,SCD患者亲属的不良心脏事件发生率很低。

国际指南建议对猝死(SCD)患者的一级亲属进行临床评估,以确定可能的死亡原因并保护幸存的亲属。只有少数研究报告了对SCD受害者亲属的临床管理和随访结果。

近日,心血管领域权威杂志International Journal of Cardiology上发表了一篇研究文章,研究人员对1995年至2016年期间转诊至丹麦奥胡斯大学医院遗传性心脏病诊室的SCD受害者亲属的临床和遗传评估进行了一项回顾性队列研究。研究人员分析了所有儿童和成人SCD病例的临床和尸检结果。对亲属随访了心血管不良事件,包括心脏住院、新发心力衰竭、冠心病、恶性晕厥或证实的恶性室性心律失常和死亡。

研究人员纳入了56名SCD受害者的292名亲属。在中位(四分位距)随访时间为3.3(1.6-4.7)年,十二名亲戚经历了不良心血管事件,其中只有五的与家庭遗传性心脏病相关。一名患者发展为扩张型心肌病和心动过速引起的心脏衰竭,五例患者出现室性心动过速或恶性晕厥,并接受了预防性植入型心律转复除颤器,三名患者发生冠心病事件,两名患者死于高龄。

由此可见,当采用基于指南的评估和护理时,SCD患者亲属的不良心脏事件发生率很低。

原始出处:

Katrine M. Müllertza,et al. Outcome of clinical management in relatives of sudden cardiac death victims.International Journal of Cardiology.2018. https://doi.org/10.1016/j.ijcard.2018.03.022

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1781884, encodeId=0c971e818848d, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Sun Aug 12 04:37:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487070, encodeId=d4b4148e070e1, content=<a href='/topic/show?id=2b902295e5b' target=_blank style='color:#2F92EE;'>#临床管理#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22957, encryptionId=2b902295e5b, topicName=临床管理)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d89d8256855, createdName=shuangle, createdTime=Sun Mar 11 06:37:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593467, encodeId=1322159346e69, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Sun Mar 11 06:37:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294576, encodeId=d2942945e634, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Mar 09 16:56:50 CST 2018, time=2018-03-09, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1781884, encodeId=0c971e818848d, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Sun Aug 12 04:37:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487070, encodeId=d4b4148e070e1, content=<a href='/topic/show?id=2b902295e5b' target=_blank style='color:#2F92EE;'>#临床管理#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22957, encryptionId=2b902295e5b, topicName=临床管理)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d89d8256855, createdName=shuangle, createdTime=Sun Mar 11 06:37:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593467, encodeId=1322159346e69, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Sun Mar 11 06:37:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294576, encodeId=d2942945e634, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Mar 09 16:56:50 CST 2018, time=2018-03-09, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1781884, encodeId=0c971e818848d, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Sun Aug 12 04:37:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487070, encodeId=d4b4148e070e1, content=<a href='/topic/show?id=2b902295e5b' target=_blank style='color:#2F92EE;'>#临床管理#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22957, encryptionId=2b902295e5b, topicName=临床管理)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d89d8256855, createdName=shuangle, createdTime=Sun Mar 11 06:37:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593467, encodeId=1322159346e69, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Sun Mar 11 06:37:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294576, encodeId=d2942945e634, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Mar 09 16:56:50 CST 2018, time=2018-03-09, status=1, ipAttribution=)]
    2018-03-11 mhm295
  4. [GetPortalCommentsPageByObjectIdResponse(id=1781884, encodeId=0c971e818848d, content=<a href='/topic/show?id=5db8409ed8' target=_blank style='color:#2F92EE;'>#Cardiol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4097, encryptionId=5db8409ed8, topicName=Cardiol)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Sun Aug 12 04:37:00 CST 2018, time=2018-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1487070, encodeId=d4b4148e070e1, content=<a href='/topic/show?id=2b902295e5b' target=_blank style='color:#2F92EE;'>#临床管理#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22957, encryptionId=2b902295e5b, topicName=临床管理)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d89d8256855, createdName=shuangle, createdTime=Sun Mar 11 06:37:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1593467, encodeId=1322159346e69, content=<a href='/topic/show?id=9850510e9a3' target=_blank style='color:#2F92EE;'>#心源性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51079, encryptionId=9850510e9a3, topicName=心源性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=955718147815, createdName=mhm295, createdTime=Sun Mar 11 06:37:00 CST 2018, time=2018-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=294576, encodeId=d2942945e634, content=学习了.谢谢分享., beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Fri Mar 09 16:56:50 CST 2018, time=2018-03-09, status=1, ipAttribution=)]
    2018-03-09 1e0f8808m18(暂无匿称)

    学习了.谢谢分享.

    0

相关资讯

Mayo Clin Proc:血钙低,心源性猝死风险增加

哈佛大学医学院Brigham妇女医院研究者发现,较低的血清钙水平增加心脏骤停的风险,即使是在正常范围。

TCT2017:重度主动脉瓣狭窄患者的心源性猝死

既往研究显示,无症状重度主动脉瓣狭窄(AS)患者心源性猝死(SCD)的年发病率约为1%。但是,这些研究大多规模较小,且为单中心研究。目前,有关重度AS患者SCD风险增加的临床预测因素的相关数据比较缺乏。本届TCT 2017大会上,“主动脉瓣狭窄与TAVR”口头报告专场,来自日本京都大学医院的Tomohiko Taniguchi等将分析和探讨重度AS患者SCD的临床预测因素。

美新版室性心律失常管理和心源性猝死预防指南十大要点

10月30日,美国心脏协会、美国心脏病学会和美国心律学会联合发布了新版室性心律失常患者管理和心源性猝死预防指南。其十大要点如下:

Int J Cardiol:成年先天性心脏病患者心源性猝死的发生率及临床特点!

由此可见,成年CHD患者发生SCD的风险仍然较高,尤其是存在复杂的基础性缺陷患者。中等到高风险病变包括艾森门格综合征、完全性大动脉转位(心房调转术或先天性矫正)和Fontan循环。

PLoS One:房颤患者心源性猝死的预测指标

在ARIC研究中,与非突发性CV死亡无关的SCD预测因子包括BMI增加,心率增加和低白蛋白。

注意:这4种情况千万别做心肺复苏!

近年来,我国心源性猝死(即因心脏病引起的心脏骤停)的发生率为41.84/10万,若以13亿人口推算,我国每年心源性猝死的总人数约为55万人。发生心源性猝死的人群绝大多数都患有器质性心脏病,其中以冠心病最为常见。