J Bone Miner Res:纤维发育不良增加乳腺癌的风险

2017-09-15 佚名 medicalxpress

乳腺癌是女性中最常见的癌症之一,威胁着全世界女性的生命,关于乳腺癌风险因素的研究比比皆是,最近,发表于《骨骼与矿物质》杂志上的一项研究指出,纤维发育不良(FD)会增加患乳腺癌的风险。

乳腺癌是女性中最常见的癌症之一,威胁着全世界女性的生命,关于乳腺癌风险因素的研究比比皆是,最近,发表于《骨骼与矿物质》杂志上的一项研究指出,纤维发育不良(FD)会增加患乳腺癌的风险。

来自荷兰莱顿大学医学中心的研究人员们使用医院记录的134名纤维发育不良女性患者数据,和121名美国纤维发育不良患者资料,评估了乳腺癌和纤维发育不良之间的关系。

研究人员发现15例乳腺癌病例,他们利用荷兰病理学注册验证乳腺癌发病率进行对比,结果发现,纤维发育不良的女性患者患乳腺癌的平均年龄在46岁,而非纤维发育不良的乳腺癌发病平均年龄则为51岁。除此之外,与荷兰一般人群相比,纤维发育不良参与者的乳腺癌风险增加3.4倍,其他胸疾病风险增加了13.2倍。乳腺癌的发病率在美国组的平均年龄36岁,与美国一般人群相比,纤维发育不良会使患乳腺癌的风险增加3.9倍,将胸疾病增加5.7倍。

研究小组负责人表示:“患乳腺癌的风险在年轻的时候就会增加,尤其是纤维发育不良的人群,会大大增加乳腺癌的风险,我们的研究表明乳腺癌筛查应考虑在这个特定的群体,在年轻的时候就进行筛选排查,最大限度的减少乳腺癌的发病率。”

原始出处:

Bas C.J. Majoor, Alison M. Boyce,  Judith V.M.G. Bovée, et.al. Increased Risk of Breast Cancer at a Young Age in Women with Fibrous Dysplasia. JBMR

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