J Gastroen Hepatol:内镜超声在直肠癌分期中的应用

2018-08-03 zhangfan MedSci原创

研究发现接受内镜超声直肠癌分期人群辅助放化疗的比例增加,但总生存率无显著提高

直肠癌患者(RC)预后与其疾病分期相关,近日研究人员考察了内镜超声(EUS)对RC治疗模式和生存率的影响。

研究人员考察2005-07年间RC患者医疗保险数据库数据,比较接受EUS和腹部及骨盆计算机断层扫描(CTAP)的患者与单独使用CTAP患者的预后及治疗手段差异。

总计3408名非转移性RC患者参与研究。相比于仅进行CTAP检测,接受EUS-CTAP检测人群年龄较低(75 vs 76岁)、男性比例更高(57.6 vs 48.7%)以及Charlson合并症得分更低(P < 0.0001)。经济情况、医生建议以及医疗资源与EUS使用率相关。EUS人群接受辅助放化疗的比例增加(50.3% vs 16.0%, P < 0.0001)、生存期延长(60 vs 57个月)但总生存率差异不显著。

研究发现接受内镜超声直肠癌分期人群辅助放化疗的比例增加,但总生存率无显著提高。

原始出处:


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    2019-06-12 许安
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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Fri Aug 03 08:37:59 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335967, encodeId=e24533596ed8, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Fri Aug 03 08:37:54 CST 2018, time=2018-08-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=335966, encodeId=107933596698, content=学习了长知识, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Fri Aug 03 08:37:30 CST 2018, time=2018-08-03, status=1, ipAttribution=)]
    2018-08-04 gwc384
  5. 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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Fri Aug 03 08:37:30 CST 2018, time=2018-08-03, status=1, ipAttribution=)]
    2018-08-03 cscdliu

    学习了,谢谢

    0

  6. 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level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201006/4db877c2887649beb09cb5effd0b38c7/916f66edd48a4e77b20ebc3e14b6e45c.jpg, createdBy=141e1980133, createdName=Y—xianghai, createdTime=Fri Aug 03 08:37:30 CST 2018, time=2018-08-03, status=1, ipAttribution=)]
    2018-08-03 龙胆草

    学习谢谢分享

    0

  7. 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    2018-08-03 Y—xianghai

    学习了长知识

    0

  8. 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    2018-08-03 Y—xianghai

    学习了长知识

    0

  9. 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    2018-08-03 Y—xianghai

    学习了长知识

    0

  10. 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    2018-08-03 Y—xianghai

    学习了长知识

    0

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结直肠癌在美国是发病第三高的癌症,在中国也是。大多数直肠癌患者都是50岁以上发病的,随着筛查的普及,这部分人群的直肠癌发病率也在逐年下降,但是50岁以下的年轻人中直肠癌发病却在上升。而且随着治疗措施的进步和筛查的普及,直肠癌的死亡率这些年下降了不少,但在50岁以下的年轻患者中死亡率却上升了。

世界首例!用“猪小肠”修补人肠

7 月 11 日,中山大学附属第六医院肛肠外科任东林教授团队宣布,他们首次运用来源于“猪小肠”的生物补片材料,为一女性患者“修补”了直肠中的“破洞”,使直肠功能在经历 11 年的“折腾”后恢复正常。据悉,“猪小肠”生物补片运用在人体直肠重建,尚属世界首例。