J Periodontol:检测牙周病和前列腺疾病患者龈下菌斑和前列腺液中的口腔致病菌

2017-08-30 MedSci MedSci原创

慢性前列腺炎(CPr)和良性前列腺增生(BPH)是复杂的炎症,其病因决定因素仍不明确。牙周炎是由口腔龈下定植细菌引起的。牙周病对前列腺炎的影响尚未确定。本研究的目的是从牙周病和CPr或BPH患者的前列腺分泌物中分离口腔病原体。

慢性前列腺炎(CPr)和良性前列腺增生(BPH)是复杂的炎症,其病因决定因素仍不明确。牙周炎是由口腔龈下定植细菌引起的。牙周病对前列腺炎的影响尚未确定。本研究的目的是从牙周病和CPr或BPH患者的前列腺分泌物中分离口腔病原体。

方法:二十四名患有CPr / BPH的男性参与了研究。对其进行完整的牙周检查,包括探诊深度,出血,牙齿松动,牙龈指数和菌斑指数,并收集前列腺分泌物用于研究。牙菌斑和前列腺分泌样品用于使用逆转录 - 聚合酶链反应分析牙龈卟啉单胞菌(Pg),中间普氏菌(Pi),牙髓螺旋体(Td)和大肠杆菌的细菌DNA。

结果:6例患者为重度,7例为中度,4例为轻度慢性牙周炎。 24例前列腺分泌物样本中有17例(70.8%)有一种或多种口腔病原体。 10例BPH中有9例,14例CPr患者中有8例在其前列腺分泌物中至少有一种口腔病原体。在17例(35.3%)患者中,6例中前列腺分泌和菌斑样本中发现Pg,15例(46.7%)患者中有7例发现Td,15例中有3例发现Td 20%)。在所有牙菌斑样品中都检测到了Pi,但未在前列腺分泌物中检测到。

结论:慢性前列腺炎和牙周病之间的关联已经通过同一个体的前列腺分泌和龈下菌斑中存在相似的细菌DNA而得到证实。

原始出处:

John Estemalik, Catherine Demko, Nabil F. Bissada, et al. Simultaneous Detection of Oral Pathogens in Subgingival Plaque and Prostatic Fluid of Men With Periodontal and Prostatic Diseases. Journal of Periodontology. 2017 September. doi: 10.1902/jop.2017.160477

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    2018-03-21 wrj0131
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  4. [GetPortalCommentsPageByObjectIdResponse(id=1799011, encodeId=816b1e9901121, content=<a href='/topic/show?id=38e0e0670ff' target=_blank style='color:#2F92EE;'>#疾病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70670, encryptionId=38e0e0670ff, topicName=疾病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c859411, createdName=hmwwww, createdTime=Sun Sep 10 02:54:00 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1694330, encodeId=c50e16943302a, content=<a href='/topic/show?id=9b558805847' target=_blank style='color:#2F92EE;'>#菌斑#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=88058, encryptionId=9b558805847, topicName=菌斑)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7a9729602115, createdName=wrj0131, createdTime=Wed Mar 21 09:54:00 CST 2018, time=2018-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2037697, encodeId=bf15203e697a9, content=<a href='/topic/show?id=30a03252461' target=_blank style='color:#2F92EE;'>#前列腺疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32524, encryptionId=30a03252461, topicName=前列腺疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e3fb2500073, createdName=124987cdm26暂无昵称, createdTime=Tue Feb 27 08:54:00 CST 2018, time=2018-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726687, encodeId=13a71e26687d3, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Mon Jun 11 04:54:00 CST 2018, time=2018-06-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282257, encodeId=5621128225edf, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Fri Sep 01 06:54:00 CST 2017, time=2017-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450621, encodeId=95161450621b0, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Fri Sep 01 06:54:00 CST 2017, time=2017-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626201, encodeId=ec8216262011b, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=32d320995014, createdName=cooco, createdTime=Fri Sep 01 06:54:00 CST 2017, time=2017-09-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=238716, encodeId=097f238e16b2, content=慢性前列腺炎和牙周病之间的关联已经通过同一个体的前列腺分泌和龈下菌斑中存在相似的细菌DNA而得到证实., beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Wed Aug 30 16:17:33 CST 2017, time=2017-08-30, status=1, ipAttribution=)]
    2018-06-11 feather89
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    2017-09-01 cooco
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    2017-08-30 有备才能无患

    慢性前列腺炎和牙周病之间的关联已经通过同一个体的前列腺分泌和龈下菌斑中存在相似的细菌DNA而得到证实.

    0

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目前研究已经报道了哮喘和口腔疾病之间的关联,包括牙周病。这项回顾性研究的目的是调查哮喘患者牙周病的风险。

盘点:近期牙周病与全身性疾病的相关性研究一览

【1】BMC Nephrol:牙周炎可增加肾病的死亡率牙周炎常见于慢性肾脏疾病(CKD)者中,但是目前仍不确定牙周病是否是CKD患者过早死亡的独立危险因素。目前各种降低CKD患者死亡率的干预措施并不尽人意,因此亟需制定新的指标。因此,本次荟萃分析旨在评估CKD患者牙周病与死亡率之间的关系。研究人员检索了PubMed、Embase、Web of Science、Scopus以及近期相关会议的摘要

J Periodontol:牙周炎发生的预测:分类,社会人口信息和健康信息的影响

牙周炎发展的预测是具有挑战性的。仅使用口腔健康相关数据,特别是在年轻人群中,可能会低估疾病风险。本研究旨在探讨以人群为基础的前瞻性队列研究的口腔、系统和社会经济数据用以评估牙周炎发展的准确性。