BMC Fam Pract:他汀类药物治疗依从性与患者风险偏好相关

2016-04-07 徐媛 MedSci原创

药物治疗依从性不佳可能对患者健康及社会卫生保健成本造成诸多不良影响。很少有研究关注风险偏好与依从性之间的关系。本研究的目的旨在评估他汀类药物治疗依从性和风险偏好之间的关系。本项研究是基于问卷调查的研究,研究人员通过网络问卷调查及登记处资料(包括他汀类药物原处方、社会人口学特点、合并症等)纳入受试者,共纳入6393人,年龄在20 - 79岁之间。风险偏好是基于健康、财务方面等4项数据来划分。与风险规

药物治疗依从性不佳可能对患者健康及社会卫生保健成本造成诸多不良影响。很少有研究关注风险偏好与依从性之间的关系。本研究的目的旨在评估他汀类药物治疗依从性和风险偏好之间的关系。

本项研究是基于问卷调查的研究,研究人员通过网络问卷调查及登记处资料(包括他汀类药物原处方、社会人口学特点、合并症等)纳入受试者,共纳入6393人,年龄在20 - 79岁之间。风险偏好是基于健康、财务方面等4项数据来划分。

与风险规避组相比,风险中性组及风险寻求组患者依从性较差,OR分别为0.8(95 %-CI 0.68-0.95)与0.83(95 %-CI 0.71-0.98)。财政风险偏好与治疗依从性无明显相关性,而且,在年轻患者与无心血管病患者中,他汀类药物治疗依从性较差。

以上研究结果表明,风险偏好与他汀类药物治疗依从性相关,而与风险规避组相比,风险中性组及风险寻求组患者依从性较差。识别患者他汀类药物治疗依从性有助于临床医生为其制定最佳治疗方案。

原始出处

Barfoed BL1, Paulsen MS2, Christensen PM3, Halvorsen PA4, Kj?r T5, Larsen ML6, Larsen PV7,8, Nielsen JB9, S?ndergaard J10, Jarb?l DE11.Associations between patients' risk attitude and their adherence to statin treatment - a population based questionnaire and register study.BMC Fam Pract. 2016 Mar 9

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    2016-04-14 李继凯

    文章不错

    0

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    2016-04-14 李继凯

    值得关注

    0

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    2016-04-09 fyxzlh

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基于他汀类药物的降低低密度脂蛋白(LDL)胆固醇试验后续研究提高了对他汀类药物的安全性和有效性的理解。检查累计心血管事件(疾病总负担)提供了他汀类药物的临床应用更好的价值。本文评估了高风险人群长期治疗后对死亡率和发病率的影响。西苏格兰冠心病预防研究是一项一级预防试验,参与者为45-64岁的高LDL胆固醇男性。6595名男性被随机分配到接受每日一次普伐他汀40毫克或安慰剂,平均4.9年。随后链接到电

Eur J Dent:他汀类药物或可改善高脂血症患者的牙周非手术治疗效果

本研究旨在探讨高血脂患者对牙周非手术治疗的反映效果,以及高血脂患者使用他汀类药物是否会影响牙周非手术治疗的疗效。

Hepatology:他汀类药物可帮助HCV患者降低肝硬化和HCC风险

他汀类药物可延迟慢性丙型肝炎(HCV)患者肝纤维化进展、降低肝细胞性肝癌(HCC)风险。但是最有效的他汀类类型和剂量是什么?研究者进行了一项研究,探究不同类型和剂量的他汀类药物对HCV患者肝纤维化和HCC的影响。研究者通过电子检索的丙肝病毒感染的退伍军人(ERCHIVES)数据库获取了2001-2014年使用抗HCV治疗的所有患者,以及肝硬化和HCC信息。使用累积限定日剂量(cDDD)测定他汀类药

JACC:他汀类药物可减少无症状外周动脉疾病患者的心血管疾病和死亡率

无症状外周动脉疾病患者减少风险的干预措施的功效证据不足。这项研究的目的是评估在这一人群中他汀类药物治疗是否减少主要心血管不良事件(MACE)和死亡率。在2006年到2013年期间,研究人员从加泰罗尼亚初级保健系统的临床记录数据库(SIDIAP)获得了数据。患者年龄在35至85岁,踝肱指数≤0.95,无临床确认的心血管疾病(CVD)。参与者被归类为他汀类药物非使用者或新使用者(首次处方或至少6个月后