Am J Gastroenterol:生活环境对炎症性肠病发病率的影响

2017-07-26 zhangfan MedSci原创

研究发现,农村生活可降低炎症性肠病的发病率,特别是对于青少年儿童。研究人员认为对于1-5岁的幼儿应多多接触农村环境

近日研究人员比较了农村或城市因素对于炎症性肠病(IBD)发病率的影响。

研究以加拿大的4个省的居民为对象,使用卫生行政数据库进行人口队列研究。研究人员对阿尔伯塔省1999 - 2008年,马尼托巴和安大略省1999 - 2010年,新斯科舍省2000 - 2008年的IBD患者进行了统计。使用泊松回归确定性别标准化发病率(每100000患者年)和事件率比(IRR)。

研究共包含6662名农村登记的IBD患者以及38905名城市患者。每100000患者年中,城市患者33.16起(95% CI 27.24–39.08),农村患者30.72起(95% CI 23.81–37.64) ,风险事假率比(IRR 0.90,95% CI 0.81–0.99)。对于10岁以下儿童,农村生活可显著降低IBD发病率(IRR 0.58,95% CI 0.43–0.73) ,而对于10–17.9 岁青少年,农村生活对IBD发病率降低的影响减弱(IRR 0.72,95% CI 0.64–0.81)。研究发现,新生儿出生后5年内,乡村田园生活可显著降低IBD风险(IRR 0.75–0.78)。

研究发现,农村生活可降低炎症性肠病的发病率,特别是对于青少年儿童。研究人员认为对于1-5岁的幼儿应多多接触农村环境。

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    2018-05-01 许安
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    2017-07-26 jihuaijun1112

    学习学习学习

    0

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    2017-07-26 Y—xianghai

    学习了新知识

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