期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (3)
Breast cancer is the leading cause of cancer deaths among females globally. The crosstalk between tumor microenvironment and neoplastic cells is the k......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (4)
Six kinds of Mo-basing nanomaterials (MoO3, MoO3@Ru, Mo-PDA, MoP(R), MoP, CNT@MoS2) were successfully synthesized, which were employed as carriers to ......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (4)
Synthesis gas fermentation using acetogenic clostridia is a rapidly increasing research area. It offers the possibility to produce platform chemicals ......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (2)
Virus removal filtration is a critical step in the manufacture of monoclonal antibody products, providing a robust size-based removal of both envelope......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (5)
Chimeric antigen receptor (CAR) T-cell therapy is growing clinically and commercially as a powerful new approach to treat cancer. Understanding how ke......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (2)
In the field of therapeutic protein production, process intensification strategies entailing higher starting cell seeding densities, can potentially i......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (5)
Glycation on lysine side chains of recombinant monoclonal antibodies (mAb) is a well-known phenomenon in manufacturing processes of biopharmaceuticals......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (2)
In biopharmaceutical process development time, cost and reliability are the relevant keywords. During the development of chromatographic processes the......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (4)
Cell culture medium (CCM) formulations are chemically defined to reduce lot-to-lot variability and complexity of the medium while still providing all ......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (1)
Currently, the mammalian biomanufacturing industry explores process intensification (PI) to meet upcoming demands of biotherapeutics while keeping pro......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (2)
We have systematically investigated six compendial nonionic detergents as potential replacements for Triton x-100 in bioprocessing applications. Use o......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (4)
In recent years, targeted gene integration (TI) has been introduced as a strategy for the generation of recombinant mammalian cell lines for the produ......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (5)
This research focuses on the construction of an affinity purification system based on Cfa DnaE split intein. Cfa DnaE intein is an artificially constr......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (5)
Glioblastoma multiforme (GBM) is a highly malignant brain tumor with a poor prognosis. The GBM microenvironment is highly heterogeneous and is compose......
期刊: BIOTECHNOLOGY PROGRESS, 2022; 38 (6)
Glaucoma is the leading cause of irreversible blindness due to increased intraocular pressure (IOP) in the eye. We have developed a novel treatment op......