NEDD8-activating enzyme inhibitor, MLN4924 (Pevonedistat) induces NOXA-dependent apoptosis through up-regulation of ATF-4

Liu, XJ; Jiang, YN; Wu, JF; Zhang, WJ; Liang, YP; Jia, LJ; Yu, JH; Jeong, LS; Li, LH

Li, LH (reprint author), Fudan Univ, Canc Inst, Shanghai Canc Ctr, 270 Dong Rd, Shanghai 200032, Peoples R China.; Jeong, LS (reprint author), Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017; 488 (1): 1

Abstract

It has been reported that MLN4924 can inhibit cell growth and metastasis in various kinds of cancer. We have reported that MLN4924 is able to inhibit ......

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