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ecDNA

2020-05-29

梅斯管理员 (审核中...)

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#髓母细胞瘤# #ecDNA#

Nature Genet：髓母细胞瘤中的ecDNA：癌基因扩增与预后关联分析

2023-12-07发表于上海

(审核中...)

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#染色体外DNA#（#ecDNA#）与#癌症#及靶向治疗耐药性有关。在剑桥大学队列中，#Barrett食管#相关早期阶段与#食管癌#晚期阶段相比，ecDNA 的发生率从24%增加到43%，这表明 ecDNA 是在癌症进展过程中持续形成的。

Nature：吴思涵等发现非癌组织中也会出现ecDNA，并促进癌症形成

2023-10-31发表于威斯康星

baoya (审核中...)

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#ecDNA#

打开抗癌新思路！Nature：ecDNA“抱团行动”促使癌基因表达扩增

2022-03-02

baoya (审核中...)

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#ecDNA#

Nature重磅：揭开癌症中的神秘突变旋风，ecDNA突变簇与10%的癌症发展有关

2022-10-22

baoya (审核中...)

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#ecDNA#

Nat Commun：“增强子劫持”事件决定神经母细胞瘤中ecDNA MYCN扩增子结构

2021-03-24

baoya (审核中...)

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#ecDNA#

Nature：肿瘤异质性和耐药性的罪魁祸首之一——ecDNA

2017-03-24

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