Gastroenterology :饮食治疗可有效减少肠易激综合征(IBS)症状

2014-03-24 姜珊 中国医学论坛报

    澳大利亚一项研究表明,低可发酵寡聚糖、二糖、单糖、多元醇(FODMAP)饮食可有效减少肠易激综合征(IBS)患者功能性胃肠道症状,支持其作为IBS的一线治疗。文章发表于《胃肠病学》[Gastroenterology 2014,146(1):67]杂志1月刊。         

澳大利亚一项研究表明,低可发酵寡聚糖、二糖、单糖、多元醇(FODMAP)饮食可有效减少肠易激综合征(IBS)患者功能性胃肠道症状,支持其作为IBS的一线治疗。文章发表于《胃肠病学》[Gastroenterology 2014,146(1):67]杂志1月刊。 该研究纳入30例IBS患者及8名相匹配的健康对照者。收集所有参与者的1周习惯饮食信息,然后将其随机分配至为期21天的低 FODMAP饮食(每餐FODMAP摄入量低于0.5g)或典型澳大利亚饮食组,经至少21天的洗脱期后,两组交叉互换。通过0~100mm视觉模拟量表 评估参与者每日症状。收集参与者第17~21天的粪便并评估其排便频率、粪便重量、含水量及英国伦敦国王学院粪便图等级。结果为,与摄入典型澳大利亚饮食 相比,摄入低FODMAP饮食的IBS患者总胃肠道症状评分较低(低FODMAP饮食为22.8分,典型澳大利亚饮食为44.9 分;P<0.001)。低FODMAP饮食时,IBS患者的腹胀、腹痛及排气症状亦减少。对照组相应症状轻微且不受饮食影响。所有IBS患者均对低 FODMAP饮食期间的大便性状较为满意,但仅腹泻为主型IB

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    2015-02-16 许安
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    2014-03-26 yulin2006
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    2014-03-26 zhouqu_8
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肠易激综合征是一组包括腹痛、腹胀、排便习惯和大便性状异常的症状群。其中,腹痛和腹部不适是肠易激综合征最核心的临床症状,其突出特点是这些症状与排便有关。如果腹痛或腹部不适在进餐后加重则可能同时伴有胃的功能紊乱,又称为功能性消化不良。肠易激综合征患者多有明显的排便习惯或粪便性状的改变,排便习惯表改变现为排便次数的增加(腹泻)或减少(便秘),或腹泻与便秘交替出现。粪便性状的改变表现为糊状便、稀水便;或干

AJG:半胱氨酸蛋白酶可能导致肠易激综合征症状

近日,来自法国的研究人员Anita Annaházi发表论文指出,腔内丝氨酸蛋白酶导致腹泻型肠易激综合征(IBS-D)患者结肠细胞旁通透性和内脏敏感性增高。其他蛋白酶,半胱氨酸蛋白酶(CPs)通过吸收上皮紧密连接蛋白增加气道通透性。在此项研究中,重点研究便秘型肠易激综合征(IBS-C),评估两组IBS患者CP水平(Ⅰ),测试IBS-C粪便上清液(fecal supernatan