JAHA:房颤患者压力反射敏感性分析

2020-12-06 MedSci原创 MedSci原创

与PAF相比,PeAF患者基线BRS更低。不管房颤的类型如何,导管消融均可抑制BRS,对PAF患者的效果要比PeAF明显。

据报道,房颤(AF)可能导致压力反射敏感性(BRS)受损。但是,持续性房颤(PeAF)和阵发性房颤(PAF)患者之间的BRS差异尚未明确。

近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员检验了以下假设:与AF患者相比,PeAF患者的BRS受损程度更大。

从2015年10月开始,共有67例患者[PAF(n=46,68.7%)和PeAF(n=21,31.3%)患者(14例[20.9%];平均年龄为65.2±10.1岁)]接受了导管消融,并纳入研究。

在窦性心律期间评估基线BRS。PeAF患者的基线BRS显著低于PAF患者(2.97 [0.52-6.62] ms/mm Hg vs. 4.70 [2.36-8.37] ms/mmHg,P=0.047)。所有患者在导管消融后BRS均显著降低(4.66 [1.80–7.37] ms/mmHg vs. 0.55 [-0.15至1.22] ms/mmHg,P<0.001)。但是,与PAF患者相比,PeAF患者由于导管消融引起的BRS抑制似乎有所减弱。没有表现出BRS抑制的患者人数在PeAF患者(3/12,25%)中明显增加,相比于PAF患者(0/46,0%,P<0.01)。

该研究的结果表明,与PAF相比,PeAF患者基线BRS更低。不管房颤的类型如何,导管消融均可抑制BRS,对PAF患者的效果要比PeAF明显。

原始出处:

Miho Miyoshi.et al.Baroreflex Sensitivity in Patients With Atrial Fibrillation.J AM HEART ASSOC.2020.https://www.ahajournals.org/doi/10.1161/JAHA.120.018019

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    2020-12-08 zhaohui6731
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  5. 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    2020-12-07 12346c4dm64暂无昵称

    0

  6. 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    2020-12-06 Lizhihua6

    学会了JAHA:房颤患者压力反射敏感性分

    0

  7. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201206/663af02effb34710ba10fcda4751a7a5/a146eb22323f4203bd75a6fb3e04b8e9.jpg, createdBy=50aa5442013, createdName=莫小贝5234, createdTime=Sun Dec 06 21:24:24 CST 2020, time=2020-12-06, status=1, ipAttribution=)]
    2020-12-06 Lizhihua6

    学会了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1957420, encodeId=0b0e195e4208a, content=<a href='/topic/show?id=cd1136938be' target=_blank style='color:#2F92EE;'>#压力反射敏感性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36938, encryptionId=cd1136938be, topicName=压力反射敏感性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d47b2500175, createdName=12498cf9m35(暂无昵称), createdTime=Mon Jun 07 16:12:18 CST 2021, time=2021-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268371, encodeId=b34212683e1fb, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, 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level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201206/a728312efe624598a164d98e9f2b6fc7/0e7e5b54de204bd6865ea2dcbc499ff1.jpg, createdBy=aeec5442031, createdName=🎈琦, createdTime=Sun Dec 06 22:16:19 CST 2020, time=2020-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031324, encodeId=aa461031324d6, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Sun Dec 06 22:12:18 CST 2020, time=2020-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=905512, encodeId=857b905512b6, content=很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201206/663af02effb34710ba10fcda4751a7a5/a146eb22323f4203bd75a6fb3e04b8e9.jpg, createdBy=50aa5442013, createdName=莫小贝5234, createdTime=Sun Dec 06 21:24:24 CST 2020, time=2020-12-06, status=1, ipAttribution=)]
    2020-12-06 🎈琦

    👍

    0

  9. 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level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201206/a728312efe624598a164d98e9f2b6fc7/0e7e5b54de204bd6865ea2dcbc499ff1.jpg, createdBy=aeec5442031, createdName=🎈琦, createdTime=Sun Dec 06 22:16:19 CST 2020, time=2020-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1031324, encodeId=aa461031324d6, content=房颤,临床上碰到很多哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=心介, createdTime=Sun Dec 06 22:12:18 CST 2020, time=2020-12-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=905512, encodeId=857b905512b6, content=很好, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201206/663af02effb34710ba10fcda4751a7a5/a146eb22323f4203bd75a6fb3e04b8e9.jpg, createdBy=50aa5442013, createdName=莫小贝5234, createdTime=Sun Dec 06 21:24:24 CST 2020, time=2020-12-06, status=1, ipAttribution=)]
    2020-12-06 心介

    房颤,临床上碰到很多哦

    0

  10. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20201206/663af02effb34710ba10fcda4751a7a5/a146eb22323f4203bd75a6fb3e04b8e9.jpg, createdBy=50aa5442013, createdName=莫小贝5234, createdTime=Sun Dec 06 21:24:24 CST 2020, time=2020-12-06, status=1, ipAttribution=)]
    2020-12-06 莫小贝5234

    很好

    0

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