Obstet Gynecol:45岁以上女性双胎妊娠结局如何?

2017-04-11 xing.T MedSci原创

在超过45岁的双胎妊娠健康妇女人群中,分娩时,这些孕妇剖宫产、先兆子痫和妊娠糖尿病发生率较高,但总体结局良好。

近日,妇产科权威杂志Obstetrics and Gynecology上发表了一研究文章,研究人员旨在调查45岁以上女性双胎妊娠结局。

这是一项在139名双胎妊娠孕妇中进行的回顾性队列研究,她们分娩时至少45岁。这些参与者于2005年至2016年期间在二级转诊中心接受过治疗。分析包括基础特征和妊娠结局,包括分娩方式、分娩时孕周、妊娠期高血压疾病、妊娠糖尿病和胎儿生长受限。研究人员采用单变量分析评估了患者特征和结局之间的相关性。

产妇平均年龄为47.3±1.9岁,其中99.3%的受试者接受了体外受精,95%的受试者使用供体卵细胞。另外,患者的基础高血压(7.2%)、肥胖(9.5%)和孕前糖尿病(1.4%)发生均较低。分娩时平均孕周为35.4孕周;在妊娠34周之前分娩的占22.3%。剖宫产(93.5%,95%可信区间为87.7-96.8%)、先兆子痫(44.6%,95%可信区间为36.3-53.3%)和妊娠糖尿病(19%,95%可信区间为13.0-26.8%)的发生率较高。50.5%的初产妇发生先兆子痫,而30.5%的孕妇发生早产(P=0.028)。白种人孕妇发生妊娠少于34周的早产儿的几率为18.1%,而非白种人的女性为30.3%(P=0.036)。

在超过45岁的双胎妊娠健康妇女人群中,分娩时,这些孕妇剖宫产、先兆子痫和妊娠糖尿病发生率较高,但总体结局良好。

原始出处:

Gerber, Rachel S, et al. Outcomes of Twin Pregnancies in Women 45 Years of Age or Older.Obstetrics & Gynecology.2017. http://journals.lww.com/greenjournal/Abstract/publishahead/Outcomes_of_Twin_Pregnancies_in_Women_45_Years_of.98447.aspx

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    2017-05-20 zhmscau
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    2017-10-29 yhy100200
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    2017-04-14 wei834766788

    学习了!!!!

    0

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    2017-04-12 lemon985

    大龄的还是不要生太危险

    0

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    2017-04-12 lyh994

    国外与国内差距这么大吗?

    0

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    2017-04-12 春暖花开8785

    技术进步,高龄双胎也可以搞定。

    0

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    2017-04-11 有备才能无患

    可以怀孕双胞胎,但是注意羊水栓塞症

    0

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