Braz Dent J:手术及非手术治疗侵袭性牙周炎的临床和微生物学评估

2020-04-19 MedSci原创 MedSci原创

本研究旨在评价手术和非手术牙周治疗在全身性侵袭性牙周炎(GAgP)治疗中的临床和微生物学效果。

本研究旨在评价手术和非手术牙周治疗在全身性侵袭性牙周炎(GAgP)治疗中的临床和微生物学效果。

 

研究纳入16例GAgP患者,采用随机分口设计。上颌四区被分配为两组:非手术治疗组(NST)和手术治疗组(ST)。评估了以下临床参数:牙菌斑指数(PI)、探诊指数(BoP)、探诊深度(PD)、临床附着水平(CAL)和牙龈边缘位置(GMP)。同时测定了龈下生物膜中的牙龈卟啉单胞菌(Pg)和伴放线聚集杆菌(Aa)的浓度。在治疗后的基线(n=16)、3(n=15)、6(n=15)和12个月(n=8)评估患者的临床和微生物参数。

 

结果显示,与NST相比,ST在12个月时能降低高PD区的PD(P<0.05),6个月时促进后牙的PD减少(P<0.05)。此外,ST组的后牙在第6个月时观察到更明显的牙龈退缩(P<0.05)。然而,ST组未能在任何时间点促进额外的CAL增益(P>0.05)。此外,微生物学评估显示,两组在所有随访期间的Aa和Pg水平无统计学差异。手术治疗促进了与GAgP治疗相似的临床获益。此外,两种治疗方法在不同的随访时间都未能降低Aa和Pg的水平。

 

原始出处:

 

Camila Camarinha da Silva CirinoHugo Felipe do Vale, et al., Clinical and Microbiological Evaluation of Surgical and Nonsurgical Treatment of Aggressive Periodontitis. Braz Dent J. Nov-Dec 2019;30(6):577-586. doi: 10.1590/0103-6440201902930.

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    2020-04-21 sunyl07
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