Hypertension:高血压、高血压前期和血压控制与认知能力下降的关联

2020-12-21 MedSci原创 MedSci原创

高血压诊断时较低和较高的年龄与不同的认知能力下降有关,而与病程无关。除高血压外,高血压前期和血压控制对于维持认知功能也可能至关重要。

高血压,尤其是中年人,与认知功能下降有关,但证据尚无定论。近日,血管权威杂志Hypertension上发表了一篇研究文章,这项研究旨在调查高血压、高血压前期、年龄、诊断时间以及血压控制是否与参与者认知能力下降有关。

这项纵向研究纳入了7063名参与者,平均基线年龄为58.9岁(2008-2010年),他们参加了第2次随访(2012-2014年)。两次随访均测量了认知能力,并通过记忆力、言语流畅性、B测验和整体认知评分的标准化评分进行评估。研究人员使用线性混合模型分析了相关性。

基线时高血压和高血压前期症状与整体认知评分下降有关。高血压与记忆力降低有关;高血压前期与流畅度降低相关。高血压诊断时超过55岁与较低的整体认知和记忆检查分数相关,而高血压诊断时小于55岁与较低的整体记忆检查分数相关。高血压的持续时间与认知功能下降的任何标志均无关。在接受治疗的个体中,基线时的血压控制与总体认知和记忆检查分数的下降呈负相关。在这个相对年轻的队列中,高血压、高血压前期和血压控制是不同认知能力下降的独立预测因子。

该研究的结果表明,高血压诊断时较低和较高的年龄与不同的认知能力下降有关,而与病程无关。除高血压外,高血压前期和血压控制对于维持认知功能也可能至关重要。

原始出处:

Sara Teles de Menezes.et al.Hypertension, Prehypertension, and Hypertension Control Association With Decline in Cognitive Performance in the ELSA-Brasil Cohort.Hypertension.2020.https://www.ahajournals.org/doi/abs/10.1161/HYPERTENSIONAHA.120.15534

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    2021-02-14 feather89
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    2021-06-12 病毒猎手

    #高血压##认知障碍#有关联,因此,降压降到一定水平,可以减轻认知障碍的风险。那么,血压为什么与认知障碍相关??值得做课题吧

    0

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    2020-12-22 王志英

    学习了

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