Lancet Planetary Health:一氧化碳大气污染显著增加心血管病死亡风险

2018-01-20 朱柳媛 中国循环杂志

我们都知道,高浓度一氧化碳中毒如煤气中毒严重威胁人类健康。其实,大气中相对低浓度的一氧化碳暴露也损害健康。

我们都知道,高浓度一氧化碳中毒如煤气中毒严重威胁人类健康。其实,大气中相对低浓度的一氧化碳暴露也损害健康。

近日,复旦大学公共卫生学院阚海东教授与中国疾病预防控制中心周脉耕研究员领衔的研究团队在柳叶刀子刊上发表的一项覆盖中国272个城市的研究表明,即便短期暴露于一氧化碳污染大气中,心血管病死亡尤其冠心病死亡风险就会显著增加,一氧化碳暴露后两天内心血管病死亡风险最高。

研究者指出,这是迄今为止在发展中国家中开展的最大规模的相关研究。大气中一氧化碳污染物主要源于机动车燃料的不充分燃烧。

分析结果显示,当天和前一天大气中一氧化碳浓度每升高1 mg/m3,心血管病死亡风险增加1.12%,冠心病死亡风险增加1.75%,脑卒中死亡风险增加0.88%。

而且,在不同城市、地区及不同性别、年龄、教育程度人群中,上述关联基本相似。另外,校正标准共同污染物后,大气中一氧化碳浓度与心血管病死亡、冠心病死亡之间的相关性仍然很强。

研究者发现,大气中一氧化碳浓度与心血管病死亡风险之间的关系并没有一个明显的阈值,也就是说他们未能得出影响心血管病死亡的大气中一氧化碳浓度最低值。




当天和前一天一氧化碳大气中一氧化碳浓度与心血管病死亡风险之间的关系

研究者指出,2013-2015年,我国272个主要城市大气中一氧化碳的年平均浓度为1.20 mg/m3,范围为0.43 mg/m3~2.45 mg/m3。



研究覆盖的我国272个主要城市

原始出处:
Cong Liu, Peng Yin, Renjie Chen, et al. Ambient carbon monoxide and cardiovascular mortality: a nationwide time-series analysis in 272 cities in China. The Lancet Planetary Health. Jan 2018, 2:e12–e18.

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    2018-12-26 shizhenshan
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    2018-07-30 howi
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