JCEM:代谢和心理特征与胃袖状切除术患者体重减轻有关

2021-03-27 MedSci原创 MedSci原创

患者基线代谢和心理特征与体重减轻独立相关,并对LSG反应有着不可忽视的影响。这些数据表明,对患者代谢和心理分析可以帮助识别更适应LSG的候选人。

腹腔镜胃袖状切除术(LSG)是公认有效的减肥手术方法,但体重减轻不明显仍可能是其主要的临床问题。迄今为止,尚无经过验证的预测指标可用于更好地进行患者选择。

近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,这项研究旨在明确基线人体测量学指标、代谢和心理特征与术后12个月总体重减轻百分比(%TWL)和过度体重减轻百分比(%EWL)之间的关联。

该研究纳入106例接受了LSG的肥胖患者,他们在接受了术前评估并在术后12个月进行了随访。

与%TWL<34%的患者相比,%TWL高于中位数(≥34%)的患者较年轻,空腹血糖和HbA1c较低,高血压患病率较低,冲动量表得分较低。当考虑%EWL时,研究人员也得到了类似的结果。多变量逐步回归分析发现,年轻、冲动量表得分较低、尿中游离皮质醇水平高和HbA1c降低与%TWL增加相关,并可以解释31.5%的结局。

由此可见,患者基线代谢和心理特征与体重减轻独立相关,并对LSG反应有着不可忽视的影响。这些数据表明,对患者代谢和心理分析可以帮助识别更适应LSG的候选人

原始出处:

Emanuele Muraca.et al.Metabolic and psychological features are associated with weight loss 12 months after sleeve gastrectomy.JCEM.2021.https://doi.org/10.1210/clinem/dgab161

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    2022-03-02 heli0118
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    2021-12-28 achengzhao
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    2021-03-28 1436749007

    我学到了很多东西谢谢老师

    0

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