JCEM:补充维生素D能不能预防2型糖尿病?

2020-08-28 MedSci原创 MedSci原创

最近的试验结果与观察性研究的大量证据相吻合,这些研究表明维生素D在调节糖尿病风险中发挥着重要作用。

在过去的十年中,维生素D已成为2型糖尿病的风险决定因素,并且补充维生素D被认为是降低糖尿病风险的一种潜在干预措施。最近,一些试验报道了补充维生素D对糖尿病前期患者预防糖尿病的作用。

近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,研究人员检索了PubMed、Embase和ClinicalTrials.gov数据库,并进行了全面的文献审查,以确定:1)最近以报告了血液维生素D[25(OH)D]水平与糖尿病之间相关性纵向观察研究为基础的Meta分析,以及2)报道了补充维生素D对糖尿病前期成人发展为糖尿病影响的临床试验。

纵向观察性研究报道,在不同人群(包括糖尿病前期患者人群)中,较高的血液25(OH)D水平与较低的患糖尿病风险之间存在高度一致的关联。针对糖尿病前期患者的试验发现,补充维生素D可降低新发糖尿病的风险。在专为预防糖尿病而设计和进行的三项大型试验中,与安慰剂相比,补充维生素D可将糖尿病前期者患发生糖尿病的风险降低10%至13%。

由此可见,最近的试验结果与观察性研究的大量证据相吻合,这些研究表明维生素D在调节糖尿病风险中发挥着重要作用。

原始出处:

Anastassios G Pittas,,et al.Vitamin D supplementation for prevention of type 2 diabetes mellitus. To D or not to D?JCEM.2020.https://academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgaa594/5897217

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    2021-03-07 smallant2015
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    2021-07-22 achengzhao
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    2020-08-30 蓝莓

    不错

    0

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    2020-08-29 ms2000000744090407

    嗯嗯

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1777977, encodeId=a6021e7797703, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Sun Mar 07 01:54:00 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063359, encodeId=0d1d2063359e2, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu Jul 22 15:54:00 CST 2021, time=2021-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=881008, encodeId=ed4488100879, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3c5410793, createdName=蓝莓, createdTime=Sun Aug 30 18:42:07 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880598, encodeId=0418880598ec, content=嗯嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77dd5414349, createdName=ms2000000744090407, createdTime=Sat Aug 29 15:20:56 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880550, encodeId=ac52880550ec, content=补充维生素D可降低新发糖尿病的风险。与安慰剂相比,补充维生素D可将糖尿病前期者患发生糖尿病的风险降低10%至13%。这个不错,大家早晨多多晒晒太阳吧,补充维生素D~, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Sat Aug 29 09:03:41 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880543, encodeId=2bb2880543f5, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4cc55389514, createdName=ms9000001804787263, createdTime=Sat Aug 29 07:14:42 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043303, encodeId=20c310433034a, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Aug 29 01:54:00 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880479, encodeId=2b0e8804e9fc, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48245414255, createdName=家乐宝, createdTime=Fri Aug 28 23:19:01 CST 2020, time=2020-08-28, status=1, ipAttribution=)]
    2020-08-29 Jessica

    补充维生素D可降低新发糖尿病的风险。与安慰剂相比,补充维生素D可将糖尿病前期者患发生糖尿病的风险降低10%至13%。这个不错,大家早晨多多晒晒太阳吧,补充维生素D~

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1777977, encodeId=a6021e7797703, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Sun Mar 07 01:54:00 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063359, encodeId=0d1d2063359e2, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu Jul 22 15:54:00 CST 2021, time=2021-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=881008, encodeId=ed4488100879, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3c5410793, createdName=蓝莓, createdTime=Sun Aug 30 18:42:07 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880598, encodeId=0418880598ec, content=嗯嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77dd5414349, createdName=ms2000000744090407, createdTime=Sat Aug 29 15:20:56 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880550, encodeId=ac52880550ec, content=补充维生素D可降低新发糖尿病的风险。与安慰剂相比,补充维生素D可将糖尿病前期者患发生糖尿病的风险降低10%至13%。这个不错,大家早晨多多晒晒太阳吧,补充维生素D~, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Sat Aug 29 09:03:41 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880543, encodeId=2bb2880543f5, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4cc55389514, createdName=ms9000001804787263, createdTime=Sat Aug 29 07:14:42 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043303, encodeId=20c310433034a, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Aug 29 01:54:00 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880479, encodeId=2b0e8804e9fc, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48245414255, createdName=家乐宝, createdTime=Fri Aug 28 23:19:01 CST 2020, time=2020-08-28, status=1, ipAttribution=)]
    2020-08-29 ms9000001804787263

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1777977, encodeId=a6021e7797703, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Sun Mar 07 01:54:00 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063359, encodeId=0d1d2063359e2, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu Jul 22 15:54:00 CST 2021, time=2021-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=881008, encodeId=ed4488100879, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3c5410793, createdName=蓝莓, createdTime=Sun Aug 30 18:42:07 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880598, encodeId=0418880598ec, content=嗯嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77dd5414349, createdName=ms2000000744090407, createdTime=Sat Aug 29 15:20:56 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880550, encodeId=ac52880550ec, content=补充维生素D可降低新发糖尿病的风险。与安慰剂相比,补充维生素D可将糖尿病前期者患发生糖尿病的风险降低10%至13%。这个不错,大家早晨多多晒晒太阳吧,补充维生素D~, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Sat Aug 29 09:03:41 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880543, encodeId=2bb2880543f5, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4cc55389514, createdName=ms9000001804787263, createdTime=Sat Aug 29 07:14:42 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043303, encodeId=20c310433034a, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Aug 29 01:54:00 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880479, encodeId=2b0e8804e9fc, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48245414255, createdName=家乐宝, createdTime=Fri Aug 28 23:19:01 CST 2020, time=2020-08-28, status=1, ipAttribution=)]
    2020-08-29 misszhang

    谢谢MedSci提供最新的资讯

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1777977, encodeId=a6021e7797703, content=<a href='/topic/show?id=eb9610265ed' target=_blank style='color:#2F92EE;'>#JCEM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10265, encryptionId=eb9610265ed, topicName=JCEM)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2a4439169927, createdName=smallant2015, createdTime=Sun Mar 07 01:54:00 CST 2021, time=2021-03-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2063359, encodeId=0d1d2063359e2, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Thu Jul 22 15:54:00 CST 2021, time=2021-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=881008, encodeId=ed4488100879, content=不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de3c5410793, createdName=蓝莓, createdTime=Sun Aug 30 18:42:07 CST 2020, time=2020-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880598, encodeId=0418880598ec, content=嗯嗯, beContent=null, objectType=article, channel=null, level=null, likeNumber=102, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=77dd5414349, createdName=ms2000000744090407, createdTime=Sat Aug 29 15:20:56 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880550, encodeId=ac52880550ec, content=补充维生素D可降低新发糖尿病的风险。与安慰剂相比,补充维生素D可将糖尿病前期者患发生糖尿病的风险降低10%至13%。这个不错,大家早晨多多晒晒太阳吧,补充维生素D~, beContent=null, objectType=article, channel=null, level=null, likeNumber=112, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211019/df01a4bfb64246379ddfef3370d04115/e1274c8eb5e440918f56f83bcfea9031.jpg, createdBy=3a345397082, createdName=Jessica, createdTime=Sat Aug 29 09:03:41 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880543, encodeId=2bb2880543f5, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=92, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4cc55389514, createdName=ms9000001804787263, createdTime=Sat Aug 29 07:14:42 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043303, encodeId=20c310433034a, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat Aug 29 01:54:00 CST 2020, time=2020-08-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=880479, encodeId=2b0e8804e9fc, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=95, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48245414255, createdName=家乐宝, createdTime=Fri Aug 28 23:19:01 CST 2020, time=2020-08-28, status=1, ipAttribution=)]
    2020-08-28 家乐宝

    0

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