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Eur Heart J：47.8万篇文章分析，炎症、生物标志物、代谢综合征、肥胖和血脂是心血管研究5大热点，基础研究缩水

2019-07-24 文韬 xu'ji 中国循环杂志

研究主题治疗基层
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欧洲心脏杂志刊发了一项大数据研究，共分析了5000本期刊2003~2014年47.8万文章，发现炎症、生物标志物、代谢综合征、肥胖和血脂是整个心血管领域研究的主题。

欧洲心脏杂志刊发了一项大数据研究，共分析了5000本期刊2003~2014年47.8万文章，发现炎症、生物标志物、代谢综合征、肥胖和血脂是整个心血管领域研究的主题。

研究者确定并标记了175个研究主题。并将文章分为人群研究、临床研究和基础研究。

研究发现，临床和人群研究大幅增长，而基础研究减小。

作者认为，研究越来越重视通过新的治疗方法改善患者的预后、风险分层和预防。

研究还发现，循证治疗、临床研究的结果和预后、心血管疾病流行病学和人群研究中的风险因素研究自2004年以来发表数量大幅增长（见下图）。

在人群研究中，关于心血管病危险因素，以及社会经济学、生活方式、营养和体力活动增幅最快。

在临床研究中，基层心血管病防治和自我管理，以及急性冠脉综合征的预后评分及预后增长速度最快。

“热门”话题还包括瓣膜病和冠状动脉疾病的新疗法以及影像学。

基础研究中，干细胞/心肌修复以及组织工程（血管、生物机械因素）论文增幅最大。

研究还发现，美国论文占30％以上，居于主导地位，其次主要是德国，英国或意大利。

然而，在2011~13年，基因和干细胞研究中，中国论文占到了17.5％。

此外，转化和创新重新定义了心血管疾病的基础研究。随着时间的推移，基础研究文章减少，但干细胞和组织工程研究以及转化研究都有了实质性的增长。细胞信号传导和基因转录是基础研究的中心课题。

研究者指出，医疗需求、资金和出版政策以及科学机遇是这些发展的潜在驱动力。

原始出处：Diane Gal,  Bart Thijs,  Wolfgang Glanzel,  Karin R Sipido. Hot topics and trends in cardiovascular research. Eur Heart J . 04 June 2019

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    2020-02-09 仁心济世

    #血管研究#

    0

  2. 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    2020-06-26 hukaixun

    #标志物#

    0

  3. 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createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 25 07:21:07 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370218, encodeId=b3b83e0218ff, content=谢谢了，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Thu Jul 25 00:03:35 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-08-30 1531eac82fm

    强

    0

  4. 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createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 25 07:21:07 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370218, encodeId=b3b83e0218ff, content=谢谢了，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Thu Jul 25 00:03:35 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-25 zhaojie88

    #ART#

    0

  5. 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createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 25 07:21:07 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370218, encodeId=b3b83e0218ff, content=谢谢了，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Thu Jul 25 00:03:35 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-25 zhouqu_8

    #综合征#

    0

  6. 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createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 25 07:21:07 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370218, encodeId=b3b83e0218ff, content=谢谢了，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Thu Jul 25 00:03:35 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-25 zhu_jun9842

    #生物标志#

    0

  7. 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topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1431583, encodeId=5877143158338, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1560836, encodeId=d242156083619, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563119, encodeId=57d8156311960, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1566845, encodeId=78ce1566845d6, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370229, encodeId=73443e0229f9, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 25 07:21:07 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370218, encodeId=b3b83e0218ff, content=谢谢了，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Thu Jul 25 00:03:35 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-25 slcumt

    #HEART#

    0

  8. 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encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Fri Jun 26 15:00:00 CST 2020, time=2020-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371987, encodeId=60ce3e198704, content=强, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/05/96698d7a635d8af9713b7aa572c73a16.jpg, createdBy=66782046001, createdName=1531eac82fm, createdTime=Fri Aug 30 00:43:06 CST 2019, time=2019-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357239, encodeId=fe6a135e23928, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, 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GetPortalCommentsPageByObjectIdResponse(id=1560836, encodeId=d242156083619, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563119, encodeId=57d8156311960, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1566845, encodeId=78ce1566845d6, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370229, encodeId=73443e0229f9, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 25 07:21:07 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370218, encodeId=b3b83e0218ff, content=谢谢了，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Thu Jul 25 00:03:35 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-25 zhu_jun9842

    #生物标志#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1812464, encodeId=1de71812464ff, content=<a href='/topic/show?id=4ad789e3093' target=_blank style='color:#2F92EE;'>#血管研究#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=89730, encryptionId=4ad789e3093, topicName=血管研究)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Sun Feb 09 13:00:00 CST 2020, time=2020-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1841412, encodeId=7abc184141259, content=<a href='/topic/show?id=18bf61953d3' target=_blank style='color:#2F92EE;'>#标志物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61953, encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Fri Jun 26 15:00:00 CST 2020, time=2020-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=371987, encodeId=60ce3e198704, content=强, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/04/05/96698d7a635d8af9713b7aa572c73a16.jpg, createdBy=66782046001, createdName=1531eac82fm, createdTime=Fri Aug 30 00:43:06 CST 2019, time=2019-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357239, encodeId=fe6a135e23928, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, 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createdBy=80d715270048, createdName=slcumt, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1566845, encodeId=78ce1566845d6, content=<a href='/topic/show?id=3c746936567' target=_blank style='color:#2F92EE;'>#生物标志#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69365, encryptionId=3c746936567, topicName=生物标志)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Thu Jul 25 16:00:00 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370229, encodeId=73443e0229f9, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 25 07:21:07 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370218, encodeId=b3b83e0218ff, content=谢谢了，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Thu Jul 25 00:03:35 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-25 1209e435m98(暂无昵称)

    学习了

    0

  10. 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createdName=1209e435m98(暂无昵称), createdTime=Thu Jul 25 07:21:07 CST 2019, time=2019-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370218, encodeId=b3b83e0218ff, content=谢谢了，学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Thu Jul 25 00:03:35 CST 2019, time=2019-07-25, status=1, ipAttribution=)]
    2019-07-25 txqjm

    谢谢了，学习

    0

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