Cardiovasc Ther:西班牙急性冠脉综合征(ACS)后双抗治疗时间?

2017-04-14 佚名 环球医学

2017年4月,发表在《Cardiovasc Ther》的由西班牙科学家进行的EPICOR研究考察了西班牙急性冠脉综合征(ACS)出院后双重抗血小板治疗(DAPT)的时间。

2017年4月,发表在《Cardiovasc Ther》的由西班牙科学家进行的EPICOR研究考察了西班牙急性冠脉综合征(ACS)出院后双重抗血小板治疗(DAPT)的时间。

介绍:ACS存活者中,DAPT时间的真实世界的国家特异性研究对改善长期预后来说非常重要。

目的:旨在调查西班牙ACS出院后的DAPT治疗时间。

结果:纳入到EPICOR(急性冠脉综合征患者抗血栓管理模式的长期随访)研究的西班牙队列中的患者数据用于分析出院后2年(根据指数事件确诊的日期确定)抗血栓药物的改变和患者特征。研究人员分析了同一阶段的死亡、冠脉事件、出血事件。总体来说,高比例的患者在2年后仍然接受DAPT(53.1%)。经历了治疗中任何出血事件的患者中,将近三分之二的患者在随访末期仍然接受DAPT。>65岁、糖尿病、药物管理的患者出院后2年继续DAPT的可能性较高。2年时,需要住院的出血事件的发生率比冠脉事件的发生率低(1.4% vs 6.6%)。与单一抗血小板治疗相比,继续DAPT的患者,其冠脉事件的数量减少,而出血事件未增加。

结论:该未选定的队列研究中,超过一半的患者ACS出院后2年继续DAPT。具有额外血管风险因素的患者中,继续DAPT者较多,这表明西班牙主治医生在减少缺血风险和出血风险上,会根据患者风险特征优先考虑缺血风险的降低。

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    2017-12-15 quxin068
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    2017-04-16 yaanren
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    2017-04-15 lemon985

    学习啦

    0

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