Br J Cancer:每天几杯咖啡或茶,可改善乳腺癌患者的生存率

2021-03-26 xiaozeng MedSci原创

咖啡和茶作为全球上消费最广泛的饮料之一。其包含了许多生物活性化合物,包括大量的咖啡因和多酚。

咖啡和茶作为全球上消费最广泛的饮料之一。其包含了许多生物活性化合物,包括大量的咖啡因和多酚。既往的报道显示,摄入咖啡和咖啡因对于胰岛素敏感性、炎症反应以及抗氧化活性均具有有益的作用,这也揭示了其或可有助于乳腺癌的预后。

而由于茶对于性激素水平的影响、抗氧化特性以及其在改善胰岛素敏感性中的作用,茶也被认为具有抗癌性。然而,目前评估咖啡和茶的摄入与乳腺癌死亡率之间相关性的流行病学研究仍有限。


在该前瞻性队列研究中,研究人员旨在探究诊断后喝咖啡和茶对于乳腺癌患者的乳腺癌特异性和全因死亡率的相关作用。

研究人员通过分析在1980年至2010年期间的NHS(护士健康研究)以及1991年至2011年期间的NHSII研究中确定的8900例I-III期的乳腺癌患者。对于诊断后每4年通过有效的食物频率问卷对诊断后的咖啡和茶摄入进行评估。


在长达30年的随访中,研究人员共记录了1054例乳腺癌特异性死亡病例和2501例总死亡病例。结果显示,诊断后的咖啡摄入量增加与乳腺癌特异性死亡率的降低相关:相比于不饮用者,每天喝3杯以上的咖啡对应着死亡风险降低25%。

患者的总咖啡和总茶消费量

研究人员同样观察到咖啡的摄入与全因总死亡率的降低相关:相比于不饮用者,每天喝2至3杯咖啡的患者的风险降低24%(HR = 0.76,95%CI = 0.66-0.87)和> 3每天喝杯可降低26%的风险。而诊断后的茶摄入与较低的全因死亡率相关:相比于不饮用者,每天喝3杯以上的茶对应着风险降低26%。


总而言之,该研究结果揭示,较高的诊断后咖啡摄入量与乳腺癌更好的总体生存率相关。诊断后饮茶量的增加也可能与患者总体生存期的提高相关


原始出处:

Farvid, M.S., Spence, N.D., Rosner, B.A. et al. Post-diagnostic coffee and tea consumption and breast cancer survival. Br J Cancer (24 March 2021).

 

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    2021-04-01 14792aa3m70暂无昵称

    可变因素太多了,感觉这些都是噱头

    0

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    2021-03-29 科研科研科研

    咖啡或茶,可改善乳腺癌患者的生存率

    0

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    2021-03-27 guoyibin
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    2021-03-27 hbwxf
  5. [GetPortalCommentsPageByObjectIdResponse(id=953027, encodeId=c26095302e08, content=可变因素太多了,感觉这些都是噱头, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=655a5227427, createdName=14792aa3m70暂无昵称, createdTime=Thu Apr 01 10:46:04 CST 2021, time=2021-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=952023, encodeId=b2df9520231a, content=咖啡或茶,可改善乳腺癌患者的生存率, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20210110/e6124a4b19bc40ce8afaae096d21126b/dd778ac260c9416eb87e7d08139507f5.jpg, createdBy=4d2f5079605, createdName=科研科研科研, createdTime=Mon Mar 29 11:22:00 CST 2021, time=2021-03-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1256823, encodeId=7365125682331, content=<a href='/topic/show?id=43706900963' target=_blank style='color:#2F92EE;'>#生存率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69009, encryptionId=43706900963, topicName=生存率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6a6043, createdName=guoyibin, createdTime=Sat Mar 27 15:03:16 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1402414, encodeId=82ac140241482, content=<a href='/topic/show?id=862e8e196a1' target=_blank style='color:#2F92EE;'>#茶#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=87196, encryptionId=862e8e196a1, topicName=茶)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/eTyQ1TyLVfyaGrflWSd1Jw4u1F68ibicmN32DE38FjEW3zTIKeFeaMUAQsjyqaL4QZ3lRibFIzziacMz9niceznOTTw/132, createdBy=03082405249, createdName=hbwxf, createdTime=Sat Mar 27 15:03:16 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1571248, encodeId=00f415e12481c, content=<a href='/topic/show?id=f42823e48d7' target=_blank style='color:#2F92EE;'>#乳腺癌患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23748, encryptionId=f42823e48d7, topicName=乳腺癌患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=37bc15724202, createdName=hanhaisha2013, createdTime=Sat Mar 27 15:03:16 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=951607, encodeId=088c95160ed4, content=是真的吗,,?, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTI1oRVNmnLI9ePd5JibicaR9Hv8PGia0r1W1XwXhGqEAXKqID1hg0MWMgsKGv1nbPXDas3AxgqyRAPBg/132, createdBy=39ae5275138, createdName=岩青, createdTime=Sat Mar 27 14:10:18 CST 2021, time=2021-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=951435, encodeId=cac5951435b6, content=在探究诊断后喝咖啡和茶对于乳腺癌患者的乳腺癌特异性和全因死亡率的相关作用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=78, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/02/7354b3539aae6a0ccb1e0fff04c12084.jpg, createdBy=205b1984786, createdName=随梦飞扬, createdTime=Fri Mar 26 19:04:41 CST 2021, time=2021-03-26, status=1, ipAttribution=)]
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    2021-03-27 岩青

    是真的吗,,?

    0

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    2021-03-26 随梦飞扬

    在探究诊断后喝咖啡和茶对于乳腺癌患者的乳腺癌特异性和全因死亡率的相关作用。

    0

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