Circulation：孕期及产后期可显著增加主动脉夹层或破裂的风险

2016-08-08 MedSci MedSci原创

既往报道过一系列妊娠期间发生主动脉夹层和破裂的病例。但是，很少有以人口为基础的研究数据来支持二者之间的关联。本研究进行了一项较差队列研究，2005-2013年间纳入年龄≥12岁分娩或流产女性。研究结果为主动脉夹层或破裂。根据孕期报告的主动脉并发症的时间，我们定义了风险期为分娩前6个月到分娩后3个月。我们比较了每一位病人在此期间主动脉并发症发生的可能性。使用条件泊松回归和稳健标准误来计算发病

既往报道过一系列妊娠期间发生主动脉夹层和破裂的病例。但是，很少有以人口为基础的研究数据来支持二者之间的关联。

本研究进行了一项较差队列研究，2005-2013年间纳入年龄≥12岁分娩或流产女性。研究结果为主动脉夹层或破裂。根据孕期报告的主动脉并发症的时间，我们定义了风险期为分娩前6个月到分娩后3个月。我们比较了每一位病人在此期间主动脉并发症发生的可能性。使用条件泊松回归和稳健标准误来计算发病率和发病率比。

4933697名女性中共有6566826名孕妇，36名女性在孕期或产后期发生了主动脉夹层或破裂，9名女性在对照期1年后发生。怀孕期间和产后期主动脉并发症的发生率为5.5/100万，而等效对照1年期间主动脉并发症的发生率为1.4/100万。与对照期1年相比，妊娠与主动脉夹层或破裂的风险明显增加相关。

总而言之，该研究表明，妊娠期和产后期女性主动脉夹层或破裂的风险升高。

原始出处：

Hooman Kamel, Mary J. Roman, Alex Pitcher and Richard B. Devereux. Pregnancy and the Risk of Aortic Dissection or Rupture: A Cohort-Crossover Analysis. Circulation. 2016;doi:10.1161/CIRCULATIONAHA.115.020627.

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继续学习

57 0
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2016-08-10 circumcision

#主动脉#

28 0
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2016-08-10 mhzhuang@stu.e

#动脉夹层#

35 0
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2016-08-09 xiaotaiyang1

做母亲好伟大

67 0
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2016-08-09 忠诚向上

好好学习

59 0
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2016-08-09 刘煜

谢谢，学习了。

22 0
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2016-08-08 1dd8c52fm63(暂无匿称)

学习学习！

26 0

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