婴儿体表及肠道微生物群影响其今后患病风险

2016-01-03 QQduhp 译 MedSci原创

在Birth Defects Research Part C:Embryo Today杂志中,克利夫兰儿童医院的Sharon Meropol博士和同事针对微生物组与儿童疾病的关系这一论点开展了研究。微生物群是指数以万亿的生活在我们的肠道、呼吸道和皮肤表面的微生物。 越来越多的证据表明,在人的生命早期破坏器微生物群可能会影响其日后的发展,并增加罹患某些疾病的可能性。今年早些时候,一项研究表明,在婴儿

在Birth Defects Research Part C:Embryo Today杂志中,克利夫兰儿童医院的Sharon Meropol博士和同事针对微生物群与儿童疾病的关系这一论点开展了研究。

微生物群是指数以万亿的生活在我们的肠道、呼吸道和皮肤表面的微生物。 

越来越多的证据表明,在人的生命早期破坏儿童的微生物群可能会影响其日后的发展,并增加罹患某些疾病的可能性。今年早些时候,一项研究表明,在婴儿3个月大时若丰富其肠道细菌种类,那么他们在1岁时出现食物过敏的风险则会降低。 

Meropol解释道,微生物群紊乱可能导致众多儿童疾病如过敏、哮喘、肥胖和自闭症样神经发育紊乱等。 

许多新近研究表明,很多因素可能有助于丰富孩子体表及肠道的微生物群如母乳喂养、阴道分娩和出生后母婴皮肤直接接触。 

去年的一项研究表明,母乳喂养可以丰富婴儿体内的微生物群,以帮助婴儿更好地成长。 

过去人们普遍认为,新生儿是出生后开始拥有微生物群的,因母体子宫是无菌。 

然而,最近的研究表明,肠道微生物群的出现始于出生之前。Meropol博士和他的同事们指出,越来越多的证据表明,儿童微生物群始于在母体子宫时。

加拿大阿尔伯塔大学Petya T. Koleva博士和他的同事们发现,对于有过敏史的女性而言,她们的孩子出生后粪便中大肠杆菌更多,因此孩子们今后患呼吸系统疾病的风险增加。Meropol博士认为,这表明研究人员不仅需要考虑婴儿的微生物群,也需要考虑他们母亲的微生物群。

我们的一些现代医学技术可以影响他们体内及体表的微生物群,并影响儿童的免疫、代谢和神经系统。她认为,婴儿和儿童医院的医务人员使用配方奶粉喂养婴儿、剖腹产、免疫接种、使用抗生素等现代干预可能对新生儿的肠道微生物群产生负面影响。 

现有证据表明,孕产妇和婴儿肠道菌群可以影响孩子的疾病风险,但是博士认为,这项研究到目前为止所得的发现只是触及表面的,是九牛一毛。 

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    2017-05-20 1e145228m78(暂无匿称)

    学习了,谢谢作者分享!

    0

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href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Tue Jan 05 09:09:00 CST 2016, time=2016-01-05, status=1, ipAttribution=)]
    2016-02-16 mengli1984

    想法挺新颖

    0

  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Feb 02 18:46:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=62912, encodeId=7b68629122d, content=收了, beContent=null, objectType=article, channel=null, level=null, likeNumber=128, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5KwlM29ic8TDJMJOiarryMIZZhTjXxyRT9lffSWpWWcWojnL7ibJwcOn99ayict8FJ9ICYmNh9swD6R4E/0, createdBy=196f1683049, createdName=收获你的美, createdTime=Tue Feb 02 18:46:00 CST 2016, time=2016-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=59083, encodeId=556559083dc, content=共存亡, beContent=null, objectType=article, channel=null, level=null, likeNumber=109, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Sun Jan 24 21:36:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56112, encodeId=7a2d5611278, content=免疫接种也有负面影响,但是孩子要接种那么多种疫苗, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue Jan 12 08:48:00 CST 2016, time=2016-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55719, 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href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Tue Jan 05 09:09:00 CST 2016, time=2016-01-05, status=1, ipAttribution=)]
    2016-02-02 收获你的美

    0

  5. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Sun Jan 24 21:36:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56112, encodeId=7a2d5611278, content=免疫接种也有负面影响,但是孩子要接种那么多种疫苗, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue Jan 12 08:48:00 CST 2016, time=2016-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55719, 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href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Tue Jan 05 09:09:00 CST 2016, time=2016-01-05, status=1, ipAttribution=)]
    2016-02-02 收获你的美

    收了

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTK29w9r0upRgxUXHNhe7bd3VxHnhBSpibMbKOjtX92zXr78SkuZfUNuADrjHiaw6uibZaEYjh9cJLzew/132, createdBy=261e1682638, createdName=1de3b290m83(暂无匿称), createdTime=Sun Jan 24 21:36:00 CST 2016, time=2016-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=56112, encodeId=7a2d5611278, content=免疫接种也有负面影响,但是孩子要接种那么多种疫苗, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLRP2D8sTDxkrGNjMqwyLUGd9Wbt6L0Yw9goia4ibPGLEx48lF9kvw86FKicbdWemTqujrf6K5WPIic8g/132, createdBy=69a11636814, createdName=ssummer, createdTime=Tue Jan 12 08:48:00 CST 2016, time=2016-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=55719, encodeId=058c55e199c, content=好棒, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=df9e1651052, createdName=三三五五, createdTime=Mon Jan 11 12:51:00 CST 2016, time=2016-01-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1281739, encodeId=c2791281e3953, content=<a href='/topic/show?id=ef315299070' target=_blank style='color:#2F92EE;'>#患病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52990, encryptionId=ef315299070, topicName=患病风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Jan 05 09:09:00 CST 2016, time=2016-01-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298828, encodeId=6dad129882818, content=<a href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Tue Jan 05 09:09:00 CST 2016, time=2016-01-05, status=1, ipAttribution=)]
    2016-01-24 1de3b290m83(暂无匿称)

    共存亡

    0

  7. 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href='/topic/show?id=2088816e487' target=_blank style='color:#2F92EE;'>#肠道微生物群#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=81674, encryptionId=2088816e487, topicName=肠道微生物群)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6e43278, createdName=yangjxjc, createdTime=Tue Jan 05 09:09:00 CST 2016, time=2016-01-05, status=1, ipAttribution=)]
    2016-01-12 ssummer

    免疫接种也有负面影响,但是孩子要接种那么多种疫苗

    0

  8. 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    2016-01-11 三三五五

    好棒

    0

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