BMJ:切昆贡亚病毒-案例报道

2017-03-16 xing.T MedSci原创

切昆贡亚病毒曾被认为是一种热带疾病,但现在其有着更广泛的地域传播。它折射了尼罗河病毒,并已成为美国地方流行性疾病。

患者为一名58岁的女护士,因发热2个月以及手和手腕小关节极度疼痛的肿胀而就诊(如图1所示)。她最近到访过肯尼亚。


该患者的C-反应蛋白水平和血浆粘度增加,并且其自身抗体检测结果为阴性。疟疾、HIV病毒、梅毒和黄病毒检测为阴性,但可以检测到切昆贡亚病毒抗体滴度上升。

切昆贡亚病毒曾被认为是一种热带疾病,但现在其有着更广泛的地域传播。它折射了尼罗河病毒,并已成为美国地方流行性疾病。

西半球的临床医生应该意识到切昆贡亚病毒感染可以导致与类风湿性关节炎类似的症状。早期识别可以避免不必要的免疫抑制药物的使用。

原始出处:

Gayathri Nayar.et al. Chikungunya.BMJ 2017; 356 doi:https://doi.org/10.1136/bmj.j250

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1848256, encodeId=506e18482567c, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 18 10:41:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180539, encodeId=0783180539fc, content=在中国病毒检测能检测出来吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQplWKnpWzLNhwt0iaysac26kHSLALtF7WSiazzKgC6sFsKh7FYjqG1U8FWFDTgMv85gMMnCbA6t9sQFI/0, createdBy=30172028796, createdName=晨起花开, createdTime=Fri Mar 17 08:36:15 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180331, encodeId=8adf180331ca, content=原始出处在哪里, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Thu Mar 16 12:49:06 CST 2017, time=2017-03-16, status=1, ipAttribution=)]
    2017-07-18 gaoxiaoe
  2. [GetPortalCommentsPageByObjectIdResponse(id=1848256, encodeId=506e18482567c, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 18 10:41:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180539, encodeId=0783180539fc, content=在中国病毒检测能检测出来吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQplWKnpWzLNhwt0iaysac26kHSLALtF7WSiazzKgC6sFsKh7FYjqG1U8FWFDTgMv85gMMnCbA6t9sQFI/0, createdBy=30172028796, createdName=晨起花开, createdTime=Fri Mar 17 08:36:15 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180331, encodeId=8adf180331ca, content=原始出处在哪里, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Thu Mar 16 12:49:06 CST 2017, time=2017-03-16, status=1, ipAttribution=)]
    2017-03-17 晨起花开

    在中国病毒检测能检测出来吗?

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1848256, encodeId=506e18482567c, content=<a href='/topic/show?id=2977356edc' target=_blank style='color:#2F92EE;'>#BMJ#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3567, encryptionId=2977356edc, topicName=BMJ)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=148754, createdName=gaoxiaoe, createdTime=Tue Jul 18 10:41:00 CST 2017, time=2017-07-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180539, encodeId=0783180539fc, content=在中国病毒检测能检测出来吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM6DGOvNrRdcib3UmzMgpEQplWKnpWzLNhwt0iaysac26kHSLALtF7WSiazzKgC6sFsKh7FYjqG1U8FWFDTgMv85gMMnCbA6t9sQFI/0, createdBy=30172028796, createdName=晨起花开, createdTime=Fri Mar 17 08:36:15 CST 2017, time=2017-03-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=180331, encodeId=8adf180331ca, content=原始出处在哪里, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Thu Mar 16 12:49:06 CST 2017, time=2017-03-16, status=1, ipAttribution=)]
    2017-03-16 雾夜芭蕾

    原始出处在哪里

    0