Am J Clin Nutr: 维生素D有助治疗儿童营养不良,显著减少运动能力、语言能力发育滞后情况

2018-05-02 佚名 新华社

维生素D对人体骨骼和肌肉健康的有益作用已经广为人知。一个国际研究小组日前发现,维生素D在帮助患有营养不良症的儿童增加体重和促进大脑发育方面也有显著作用。

维生素D对人体骨骼和肌肉健康的有益作用已经广为人知。一个国际研究小组日前发现,维生素D在帮助患有营养不良症的儿童增加体重和促进大脑发育方面也有显著作用。

来自巴基斯坦旁遮普大学和伦敦大学玛丽皇后学院的研究人员在新一期《美国临床营养学杂志》上报告说,他们在巴基斯坦开展的一项研究表明,患有营养不良症的儿童在服用高剂量维生素D后体重增加明显,维生素D还能显著减少他们出现运动能力、语言能力发育延迟的现象。

临床试验中,185名6到58月龄、患有营养不良症的巴基斯坦儿童在接受高能量饮食治疗的同时,被随机分为两组,其中一组服用安慰剂,而另一组每日两次口服剂量为5毫克的维生素D,这一剂量远超过正常人的每日需求量。

8周后,服用维生素D的那组儿童体重增加明显,比对照组儿童平均多增重0.26公斤。此外补充维生素D还能显著减少这些儿童出现运动能力、语言能力发育滞后的情况。目前并没有发现高剂量维生素D导致的明显不良反应,但研究人员表示还将进一步试验,以排除该补充剂在临床上可能出现的副作用。

伦敦大学玛丽皇后学院的阿德里安·马蒂诺教授表示,这是首次在人体临床试验中验证维生素D对大脑发育的影响,该结果印证了此前认为维生素D对人体中枢神经系统有重要作用的理论。

研究人员表示,这一成果对治疗严重营养不良症有重大意义,目前全球约有2千万儿童受严重营养不良影响,导致身体和智力发育滞后。

原始出处:

Javeria Saleem, Rubeena Zakar, Muhammad Z Zakar, et.al. High-dose vitamin D3 in the treatment of severe acute malnutrition: a multicenter double-blind randomized controlled trial. The American Journal of Clinical Nutrition, Volume 107, Issue 5, 1 May 2018

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    2018-11-09 zutt
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    2018-05-11 haige

    学习了!

    0

  4. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed May 02 18:33:54 CST 2018, time=2018-05-02, status=1, ipAttribution=)]
    2018-05-04 neurowu
  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed May 02 18:33:54 CST 2018, time=2018-05-02, status=1, ipAttribution=)]
    2018-05-04 yangjxjc
  6. 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  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu May 03 12:44:38 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311358, encodeId=56d0311358cc, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed May 02 18:59:10 CST 2018, time=2018-05-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311352, encodeId=1bc131135237, content=学习了.谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed May 02 18:33:54 CST 2018, time=2018-05-02, status=1, ipAttribution=)]
    2018-05-04 yfjms

    学习

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu May 03 12:44:38 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311358, encodeId=56d0311358cc, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed May 02 18:59:10 CST 2018, time=2018-05-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311352, encodeId=1bc131135237, content=学习了.谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed May 02 18:33:54 CST 2018, time=2018-05-02, status=1, ipAttribution=)]
    2018-05-03 惠映实验室

    学习了.谢谢分享.

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=2040521, encodeId=af1f20405217b, content=<a href='/topic/show?id=2cb02845984' target=_blank style='color:#2F92EE;'>#儿童营养#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28459, encryptionId=2cb02845984, topicName=儿童营养)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=742793, createdName=zutt, createdTime=Fri Nov 09 07:46:00 CST 2018, time=2018-11-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1972080, encodeId=d89b19e2080df, content=<a href='/topic/show?id=8bec918233e' target=_blank style='color:#2F92EE;'>#语言能力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91823, encryptionId=8bec918233e, topicName=语言能力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8306486, 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createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Thu May 03 12:44:38 CST 2018, time=2018-05-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311358, encodeId=56d0311358cc, content=学习一下谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzaiabIFicf63hKvVMjL6aJlx4yX4UcXmzX9DyibCRcicq0QtCRWMaQKh8MYjE1D3EKUBopgiaGWYuqbeR/0, createdBy=0c2b1999806, createdName=三生有幸9135, createdTime=Wed May 02 18:59:10 CST 2018, time=2018-05-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=311352, encodeId=1bc131135237, content=学习了.谢谢作者分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed May 02 18:33:54 CST 2018, time=2018-05-02, status=1, ipAttribution=)]
    2018-05-02 三生有幸9135

    学习一下谢谢分享

    0

  10. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed May 02 18:33:54 CST 2018, time=2018-05-02, status=1, ipAttribution=)]
    2018-05-02 虈亣靌

    学习了.谢谢作者分享!

    0

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孕妇怀孕期间补充VD,VE和锌可减少儿童喘息的发病风险据一项荟萃分析研究表明,孕妇怀孕期间补充维生素D、维生素E以及锌可降低后代儿童时期喘息的发病风险。但是研究人员表示,该研究并未确定孕妇补充VD,VE以及锌对后代哮喘和其他过敏性疾病发生的影响。来自智力天主教大学医学院的Andrea A. Beckhaus博士及其同事进行了这项荟萃分析,以确定孕妇怀孕期间营养的摄入与其后代哮喘,喘息以及其他过敏性

Neurology:维生素D缺乏导致女性多发性硬化风险升高

研究认为,维生素D缺乏是多发性硬化的风险因素

BMJ:日本大型队列研究证实循环维生素D浓度升高可降低全身以及肝特异性肿瘤风险

这项大规模队列研究证实,维生素D浓度升高可降低肿瘤风险,本研究结果支持维生素D对肿瘤的预防效果

SCI REP:维生素D补充改善了CHC患者肝纤维化发生相关的血清标志物!

通过使用CHC患者为模型,研究提供了更多的证据表明VD在肝脏纤维化的逆转过程中起着重要的作用。

BMJ:循环维生素D浓度与7种主要肿瘤风险关系研究

研究认为循环维生素D浓度与各种类型癌症的风险之间存不存在线性因果关系,研究不支持维生素D缺乏症筛查和维生素D补充作为预防原发性癌症的策略

BMJ:还在妄想通过补钙预防骨折吗?

补钙并不能有效预防骨折,不管是通过饮食、牛奶,还是钙片等保健品,不管有没有含VD,均不能有效预防骨折。