Clin Gastroenterol Hepatol:县级城市经济繁荣发展速度影响当地成年人肝病相关死亡率!

2021-09-04 Nebula MedSci原创

县级城市的经济繁荣的变化,独立于其他县级临床、人口统计学和护理可获得性等变量之外,可能与处于工作年龄的人群的肝病相关死亡率变化趋势密切相关

县级肝病相关死亡率存在显著差异。虽然人口统计学、肝病风险因素和专科肝病治疗的可获得性可以解释部分这种差异。经济繁荣程度是否会影响肝病相关死亡率尚不明确。本研究尝试探索县级繁荣程度的变化与肝病相关死亡率之间的相关性。

这是一项回顾性队列研究,收集了来自CDC的县级死亡率数据、来自贫困社区指数的经济繁荣指标、县级人口统计指标、肝病危险因素和医疗护理的获得性相关信息数据。主要分析集中于20-64岁的成年人。使用广义线性混合模型(GLMM)分析根据年龄调整后的肝病相关死亡率与经济繁荣变化之间的相关性。

经济繁荣程度不同的县级城市的肝病相关死亡率变化

分析结果显示,县级经济繁荣程度的变化与县级根据年龄调整后的肝病相关死亡率的变化呈负相关性(如,经济繁荣程度增长最少的县,与肝病相关死亡率的年增长率最大,即经济增长的越慢,肝病相关死亡率的增加就越快)。在纳入了县级协变量的GLMM模型中,经济繁荣与每年肝病相关死亡率之间仍存在显著关联(如,经济繁荣每增加10个点,每年肝病相关死亡率就多降低0.65%,p=0.006)。

综上,县级城市的经济繁荣的变化,独立于其他县级临床、人口统计学和护理可获得性等变量之外,可能与处于工作年龄的人群的肝病相关死亡率变化趋势密切相关

原始出处:

Khatana Sameed Ahmed M,Goldberg David Seth,Changes in County-Level Economic Prosperity is Associated with Liver Disease-Related Mortality Among Working-Age Adults.[J] .Clin Gastroenterol Hepatol, 2021, https://doi.org/10.1016/j.cgh.2021.08.023

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    2022-07-11 许安
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    2021-09-06 gwc384
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    2021-09-04 SR~young海东

    关注肝病

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