JCEM:2006-2016年美国儿童糖尿病酮症酸中毒入院的全国趋势

2021-05-08 MedSci原创 MedSci原创

美国儿童DKA入院率上升了40%,弱势群体风险最高。进一步的研究应归纳这些人群所面临的挑战,以为制定减轻其DKA风险的干预措施提供参考,并解决全国范围内DKA发生率上升的问题。

在美国,糖尿病酮症酸中毒(DKA)的发病率正在上升。先前的研究表明,年轻人群的患病率较高,但是尚无研究评估DKA在儿童中的全国趋势以及各亚组之间的差异。

近日,内分泌和代谢性疾病领域权威杂志Journal of Clinical Endocrinology & Metabolism上发表了一篇研究文章,研究人员试图明确儿童中DKA的全国趋势。

研究人员使用了2006年、2009年、2012年和2016年的儿童住院数据库(KID)在全国代表性的20岁以下青少年入院样本中确定了儿童DKA入院情况。研究人员估计了所有住院和人群分组中每10000例患者中DKA的住院情况,以及每10000人群、费用、住院时间(LOS)以及随时间变化趋势。研究人员使用回归模型来评估亚组随时间变化的DKA发生率的差异。

2006年至2016年之间,DKA入院人数为149535人。未经调整的每次DKA入院率从2006年的120.5人(95%CI:115.9–125.2)增加到2016年的217.7人(95%CI:208.3–227.5)。每次入院的平均费用从2006年的$14548(95%CI:$ 13971–$15125)增加至2016年的$20997(95%CI:$19973–$22022),而平均LOS从2.51(95%CI:2.45-2.57)天减少到2.28(95%CI:2.23-2.33)天。来自非城市地区的18-20岁黑人女性DKA发生率较高,她们没有私人保险,收入较低。随着时间的推移,来自非城市地区的没有私人保险的年轻男性DKA发病率上升程度较快。

由此可见,美国儿童DKA入院率上升了40%,弱势群体风险最高。进一步的研究应归纳这些人群所面临的挑战,以为制定减轻其DKA风险的干预措施提供参考,并解决全国范围内DKA发生率上升的问题

原始出处:

Estelle M Everett.et al.National Trends in Pediatric Admissions for Diabetic Ketoacidosis, 2006-2016.JCEM.2021.https://doi.org/10.1210/clinem/dgab290

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  5. 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createdName=tanxingdoctor, createdTime=Sat May 08 13:08:24 CST 2021, time=2021-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043595, encodeId=ade810435956e, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat May 08 12:38:51 CST 2021, time=2021-05-08, status=1, ipAttribution=)]
    2021-07-28 smallant2015
  6. 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  7. 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createdName=tanxingdoctor, createdTime=Sat May 08 13:08:24 CST 2021, time=2021-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043595, encodeId=ade810435956e, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat May 08 12:38:51 CST 2021, time=2021-05-08, status=1, ipAttribution=)]
    2021-05-10 mashirong
  8. 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  9. [GetPortalCommentsPageByObjectIdResponse(id=2063432, encodeId=a84e206343290, content=<a href='/topic/show?id=14fb10264d7' target=_blank style='color:#2F92EE;'>#JCE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10264, encryptionId=14fb10264d7, topicName=JCE)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e656479, createdName=achengzhao, createdTime=Fri Feb 11 09:38:51 CST 2022, time=2022-02-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1676175, encodeId=05ca16e6175c5, content=<a href='/topic/show?id=6bac955861e' target=_blank style='color:#2F92EE;'>#酸中毒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=95586, encryptionId=6bac955861e, topicName=酸中毒)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdName=tanxingdoctor, createdTime=Sat May 08 13:08:24 CST 2021, time=2021-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043595, encodeId=ade810435956e, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat May 08 12:38:51 CST 2021, time=2021-05-08, status=1, ipAttribution=)]
    2021-05-08 tanxingdoctor

    学习啦

    0

  10. 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createdName=tanxingdoctor, createdTime=Sat May 08 13:08:24 CST 2021, time=2021-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1043595, encodeId=ade810435956e, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Sat May 08 12:38:51 CST 2021, time=2021-05-08, status=1, ipAttribution=)]
    2021-05-08 misszhang

    谢谢MedSci提供最新的资讯

    0

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