J Periodontal Implant Sci:富血小板血浆对犬再植的作用

2018-10-15 MedSci MedSci原创

本研究旨在评估富血小板血浆(PRP)对再植根表面牙周愈合再组织学和组织形态学上的影响。 使用来自6只杂种狗的总共36根下颌切牙和前磨牙根。将根随机分为3组:1)阳性对照组(n = 12),保留牙周韧带(PDL)和牙骨质,将根浸泡在盐水中;2)阴性对照组(n = 12),其中去除PDL和牙骨质并将根浸泡在盐水中;3)实验组(n = 12),其中去除PDL和牙骨质并将根浸泡在PRP中。浸泡根表面

本研究旨在评估富血小板血浆(PRP)对再植根表面牙周愈合再组织学和组织形态学上的影响。

使用来自6只杂种狗的总共36根下颌切牙和前磨牙根。将根随机分为3组:1)阳性对照组(n = 12),保留牙周韧带(PDL)和牙骨质,将根浸泡在盐水中;2)阴性对照组(n = 12),其中去除PDL和牙骨质并将根浸泡在盐水中;3)实验组(n = 12),其中去除PDL和牙骨质并将根浸泡在PRP中。浸泡根表面后,将提取的根重新植入拔牙窝中。使用冠向覆位瓣覆盖根部。

组织学上,在4周实验组和阳性对照组中观察到不规则厚度的PDL样和牙骨质样组织。在8周时观察到具有更均匀厚度的PDL样组织和牙骨质样组织。在阴性对照组中,很少发现PDL样组织和牙骨质样组织,并观察到牙根吸收和粘连。在横断面组织形态学分析中,实验组在4周和8周时表现出比正和负对照组更高的牙骨质样组织形成率和更低的牙根粘连率。虽然3组牙根粘连率和牙骨质样组织形成有明显差异(P <0.05),但在任何一组之间均未观察到统计学意义(P> 0.017)。

综上所述,该研究结果表明,在犬再植期间将PRP应用于牙根表面可以减少牙根粘连,并增加PDL样和牙骨质样组织形成。

原始出处:

Jun-Mo Yang, Keon-Il Yang, et al., Effects of platelet-rich plasma on tooth replantation in dogs: a histologic and histomorphometric analysis. J Periodontal Implant Sci. 2018 Aug; 48(4): 224–235.

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    2019-09-10 feather89
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    2019-08-31 xuyu
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    2019-09-27 xuyong536
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    2018-10-15 1ddf0692m34(暂无匿称)

    学习了,长知识

    0