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Fertil Steril：IVF妊娠结局下降与BMI的关系

2015-12-15 candy 译 MedSci原创

IVFBMI妊娠结局多囊卵巢综合症
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目的：研究BMI对新鲜自体循环IVF结局的影响。设计：回顾性队列研究。设备：无。对象：共纳入来自辅助生殖技术学会从2008年-2010年的239127例鲜胚移植的患者，根据世界卫生组织的体重指数分层。正常BMI（18.5-24.9 kg/m2）被纳入到参照组（REF）。亚组研究单纯性多囊卵巢综合症的周期。干预：无主要测量结果：着床率、临床妊娠率、妊娠率、妊娠后流产率、生存率。结果：成功率和调整95

目的：研究BMI对新鲜自体循环IVF结局的影响

设计：回顾性队列研究

设备：无

对象：共纳入来自辅助生殖技术学会从2008年-2010年的239127例鲜胚移植的患者，根据世界卫生组织的体重指数分层。正常BMI（18.5-24.9 kg/m2）被纳入到参照组（REF）。亚组研究单纯性多囊卵巢综合症的周期。

干预：无

主要测量结果：着床率、临床妊娠率、妊娠率、妊娠后流产率、生存率。


结果：成功率和调整95%CI的OR显示：低和正常BMI组中妊娠结局趋向良好，而随着BMI指数的增加，妊娠结局趋向恶化。另外肥胖对PCOS患者和男性因素不孕的IVF结局呈负相关，虽然这一点并未达到统计学意义。

结论：鲜胚自体循环的成功率（包括那些专门为PCOS和男性因素不孕者）在低和正常BMI指数的人群中显得最高。而且，在高BMI指数的人群中，显示有一个渐进的和有明显统计学意义的结论，即BMI越高，结局越糟糕。今后需要探索BMI影响IVF成功率的原因，并且扩展到针对其他患者群体的研究。

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    2016-03-24 三毛坨

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    2016-03-24 三毛坨

    婆婆啪啪啪

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=73597, encodeId=57dbe3597fb, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73598, encodeId=b0cde3598a5, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73599, encodeId=1128e35998c, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73600, encodeId=9024e360052, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73601, encodeId=ec3be360114, content=i快快快, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73602, encodeId=4e04e360293, content=哈哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73592, encodeId=c4bde35921a, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73593, encodeId=3654e359371, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73594, encodeId=a7a7e359478, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73595, encodeId=277ce35953c, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=)]
    2016-03-24 三毛坨

    i快快快

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=73597, encodeId=57dbe3597fb, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73598, encodeId=b0cde3598a5, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73599, encodeId=1128e35998c, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73600, encodeId=9024e360052, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73601, encodeId=ec3be360114, content=i快快快, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73602, encodeId=4e04e360293, content=哈哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73592, encodeId=c4bde35921a, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73593, encodeId=3654e359371, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73594, encodeId=a7a7e359478, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73595, encodeId=277ce35953c, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=)]
    2016-03-24 三毛坨

    哈哈哈哈

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=73597, encodeId=57dbe3597fb, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73598, encodeId=b0cde3598a5, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73599, encodeId=1128e35998c, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73600, encodeId=9024e360052, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73601, encodeId=ec3be360114, content=i快快快, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73602, encodeId=4e04e360293, content=哈哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73592, encodeId=c4bde35921a, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73593, encodeId=3654e359371, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73594, encodeId=a7a7e359478, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73595, encodeId=277ce35953c, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=)]
    2016-03-24 三毛坨

    噼噼啪啪

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=73597, encodeId=57dbe3597fb, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73598, encodeId=b0cde3598a5, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73599, encodeId=1128e35998c, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=116, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73600, encodeId=9024e360052, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=120, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73601, encodeId=ec3be360114, content=i快快快, beContent=null, objectType=article, channel=null, level=null, likeNumber=98, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73602, encodeId=4e04e360293, content=哈哈哈哈, beContent=null, objectType=article, channel=null, level=null, likeNumber=88, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:20:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73592, encodeId=c4bde35921a, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73593, encodeId=3654e359371, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=90, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73594, encodeId=a7a7e359478, content=婆婆啪啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=139, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=73595, encodeId=277ce35953c, content=噼噼啪啪, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=43f41674911, createdName=三毛坨, createdTime=Thu Mar 24 17:19:00 CST 2016, time=2016-03-24, status=1, ipAttribution=)]
    2016-03-24 三毛坨

    婆婆啪啪啪

    0

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    2016-03-24 三毛坨

    婆婆啪啪啪

    0

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    2016-03-24 三毛坨

    噼噼啪啪

    0

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