Obstet Gynecol:双胞胎妊娠—哪种分娩方式更佳?

2017-05-23 佚名 环球医学

2017年2月,发表在《Obstet Gynecol》的一项由美国科学家进行的研究考察了双胞胎妊娠中,计划分娩方式和产妇发病率之间的相关性。

2017年2月,发表在《Obstet Gynecol》的一项由美国科学家进行的研究考察了双胞胎妊娠中,计划分娩方式和产妇发病率之间的相关性。

目的:旨在根据计划分娩方式评估双胞胎妊娠中的产妇发病率

方法:研究人员组建了7年回顾性队列(2007~2014),队列由妊娠32周或超过妊娠32周的可分娩的胎头先露双胞胎的女性组成,这些女性无分娩禁忌或瘢痕子宫。研究人员将女性分为尝试阴道分娩或选择择期剖宫产的女性。首要结局为产妇发病的测量的复合,包括死亡、产后出血、感染、大手术、因感染或再手术而再住院、因出血或感染而需要退出研究和扩大样本量、静脉血栓栓塞、小肠梗阻或肠梗阻、入住重症监护单元。产后出血的定义为估计血流失≥1500mL,或需要输血。研究人员也确定了每组的裂伤率。使用逻辑回归控制混杂因素,根据计划分娩方式检测产妇发病的几率。

结果:妊娠32周或超过妊娠32周的2272个双胞胎妊娠中,1140例(50%)满足入组标准,其中571人(50%)择期剖宫产,569人(50%)尝试阴道分娩。选择阴道分娩的女性中,有74%(418人)实现了双胞胎都阴道分娩。阴道分娩组和剖宫产组的产妇发病率分别为12.3%和9.1%(P=0.08;调整比值比OR,1.6;95% CI,1.1~2.4)。阴道分娩(52人)比剖宫产(28人)的女性更常发生产后出血,两组发生率分别为9.1%和4.9%(P<0.01;调整OR,2.2;95% CI,1.4~3.6),这也是造成两组复合发病率差异的主要原因。

结论:当调整了潜在混杂因素后,阴道分娩的女性比择期剖宫产的女性发生产妇发病的几率高,主要由于出血造成。在实际情况下,74%的阴道分娩机会可换来严重产后出血率绝对增加4%。

原始出处:

Easter SR, Robinson JN, Lieberman E, et al. Association of Intended Route of Delivery and Maternal Morbidity in Twin Pregnancy. Obstet Gynecol. 2017 Feb;129(2):305-310. doi: 10.1097/AOG.0000000000001844.

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    2017-07-01 智者为医08
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    2018-01-31 yhy100200
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    2017-05-25 linlin2312
  5. [GetPortalCommentsPageByObjectIdResponse(id=2043962, encodeId=5553204396283, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Sat Jul 01 22:10:00 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011300, encodeId=ed42201130039, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Wed Jan 31 21:10:00 CST 2018, time=2018-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693885, encodeId=0a25169388536, content=<a href='/topic/show?id=9e633154e6b' target=_blank style='color:#2F92EE;'>#分娩方式#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31547, encryptionId=9e633154e6b, topicName=分娩方式)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d929475476, createdName=stfoxst, createdTime=Sat Nov 04 12:10:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275107, encodeId=946012e51074a, content=<a href='/topic/show?id=263031541b4' target=_blank style='color:#2F92EE;'>#分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31541, encryptionId=263031541b4, topicName=分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Thu May 25 06:10:00 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1393897, encodeId=a34e139389ea0, content=<a href='/topic/show?id=32313e5765b' target=_blank style='color:#2F92EE;'>#双胞胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37576, encryptionId=32313e5765b, topicName=双胞胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a5c2500147, createdName=12498bb3m90(暂无昵称), createdTime=Thu May 25 06:10:00 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201797, encodeId=3f4d201e9762, content=学习并分享,提高了认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Wed May 24 00:14:09 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201723, encodeId=5a48201e238a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6EF3hKja8nER8RMzxQdria9eCYFhgLTLsDOeqnvIYdeLDz5eP6EnicLuE5gibiawgno4zUA0jAR7Nbtp2llQ9fs3Mk/0, createdBy=278f1986883, createdName=医鸣惊人, createdTime=Tue May 23 18:54:28 CST 2017, time=2017-05-23, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2043962, encodeId=5553204396283, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Sat Jul 01 22:10:00 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011300, encodeId=ed42201130039, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Wed Jan 31 21:10:00 CST 2018, time=2018-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693885, encodeId=0a25169388536, content=<a href='/topic/show?id=9e633154e6b' target=_blank style='color:#2F92EE;'>#分娩方式#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31547, encryptionId=9e633154e6b, topicName=分娩方式)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d929475476, createdName=stfoxst, createdTime=Sat Nov 04 12:10:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275107, encodeId=946012e51074a, content=<a href='/topic/show?id=263031541b4' target=_blank style='color:#2F92EE;'>#分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31541, encryptionId=263031541b4, topicName=分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Thu May 25 06:10:00 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1393897, encodeId=a34e139389ea0, content=<a href='/topic/show?id=32313e5765b' target=_blank style='color:#2F92EE;'>#双胞胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37576, encryptionId=32313e5765b, topicName=双胞胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a5c2500147, createdName=12498bb3m90(暂无昵称), createdTime=Thu May 25 06:10:00 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201797, encodeId=3f4d201e9762, content=学习并分享,提高了认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Wed May 24 00:14:09 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201723, encodeId=5a48201e238a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6EF3hKja8nER8RMzxQdria9eCYFhgLTLsDOeqnvIYdeLDz5eP6EnicLuE5gibiawgno4zUA0jAR7Nbtp2llQ9fs3Mk/0, createdBy=278f1986883, createdName=医鸣惊人, createdTime=Tue May 23 18:54:28 CST 2017, time=2017-05-23, status=1, ipAttribution=)]
    2017-05-24 杨利洪

    学习并分享,提高了认识

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2043962, encodeId=5553204396283, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Sat Jul 01 22:10:00 CST 2017, time=2017-07-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011300, encodeId=ed42201130039, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Wed Jan 31 21:10:00 CST 2018, time=2018-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1693885, encodeId=0a25169388536, content=<a href='/topic/show?id=9e633154e6b' target=_blank style='color:#2F92EE;'>#分娩方式#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31547, encryptionId=9e633154e6b, topicName=分娩方式)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=00d929475476, createdName=stfoxst, createdTime=Sat Nov 04 12:10:00 CST 2017, time=2017-11-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1275107, encodeId=946012e51074a, content=<a href='/topic/show?id=263031541b4' target=_blank style='color:#2F92EE;'>#分娩#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31541, encryptionId=263031541b4, topicName=分娩)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d590125, createdName=linlin2312, createdTime=Thu May 25 06:10:00 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1393897, encodeId=a34e139389ea0, content=<a href='/topic/show?id=32313e5765b' target=_blank style='color:#2F92EE;'>#双胞胎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37576, encryptionId=32313e5765b, topicName=双胞胎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7a5c2500147, createdName=12498bb3m90(暂无昵称), createdTime=Thu May 25 06:10:00 CST 2017, time=2017-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201797, encodeId=3f4d201e9762, content=学习并分享,提高了认识, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/21/39b6a0099eb602e8ac1f7e10d5d440a9.jpg, createdBy=dee01724555, createdName=杨利洪, createdTime=Wed May 24 00:14:09 CST 2017, time=2017-05-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=201723, encodeId=5a48201e238a, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6EF3hKja8nER8RMzxQdria9eCYFhgLTLsDOeqnvIYdeLDz5eP6EnicLuE5gibiawgno4zUA0jAR7Nbtp2llQ9fs3Mk/0, createdBy=278f1986883, createdName=医鸣惊人, createdTime=Tue May 23 18:54:28 CST 2017, time=2017-05-23, status=1, ipAttribution=)]
    2017-05-23 医鸣惊人

    学习了

    0

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