PLOS Genet:天生夜猫子?可能跟基因有关

2017-12-20 佚名 煎蛋网

美国心肺血液研究所的科学家称,如果人类身上也有相似的基因,或许科学家能够发明新的方法解决一些睡眠问题,如失眠症和嗜睡症等。主要研究员 Susan Harbison 说道,“这个研究将能帮助我们解决生物学中的一个重大谜团:那就是人类的睡眠需求。每个人的睡眠需求不一样,这让我们难以摸清睡眠的意义。” 研究与结果

每个人每天所需要的睡眠时长是不一样的,但这跟我们的基因有关系吗?最近,科学家对果蝇的研究或许能解释这一点。果蝇的一些基因似乎与它们的睡眠时长有所联系,而这些基因也与大脑发育、学习和记忆有关。

美国心肺血液研究所的科学家称,如果人类身上也有相似的基因,或许科学家能够发明新的方法解决一些睡眠问题,如失眠症和嗜睡症等。主要研究员 Susan Harbison 说道,“这个研究将能帮助我们解决生物学中的一个重大谜团:那就是人类的睡眠需求。每个人的睡眠需求不一样,这让我们难以摸清睡眠的意义。”

研究与结果

科学家让爱睡觉的果蝇彼此交配,又让不爱睡觉的那些也彼此交配,最终通过 13 代野生果蝇培育出了两组不同的蝇:一组贪睡的和一组睡得少的。

第一代果蝇的平均睡眠时长都是每天 450 分钟左右。到了第 13 代,睡眠时间长的果蝇平均每天大概要睡 700 分钟,另一组则连 100 分钟都不需要——100 分钟可能连看部电影都不够!通过比较,科学家发现这两组果蝇有 80 个基因出现了不同,不同之处有 126 个。

果蝇不仅有很多跟人类相同的基因,而且培养起来不需要多大功夫,寿命也短,所以是最佳实验对象。

Harbison 说道,跟很多研究不一样,他们在这次研究中用到的是自然界中的现存基因,而不是特意让果蝇的基因发生变异。直到现在,科学家都不知道自然界中会不会出现这种极端的睡眠时长。

科学家在这次研究中还发现,两组果蝇的寿命并没有太大区别。似乎只要睡眠时间符合需求,就不会对生理表现产生睡眠影响,至少对果蝇来说正是如此。

研究意义

虽然这项研究并没有什么惊人的发现,但至少我们可以略微知道,基因对睡眠需求的影响,以及其与身体生理周期有何关系。另外,我们也可以知道,遗传变异到底可以从何种程度上影响睡眠需求。

之前已经有研究发现,某种基因变异会让人们变成“夜猫子”,而人体中还有 7 种基因与失眠问题有关。通过这些研究,我们或许最终可以找到睡眠问题的解决方法。

该研究发表在 PLOS Genetics 上。

原始出处:

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    2018-05-29 cy0324
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    2017-12-21 周周人

    学习.

    0

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    2017-12-20 有备才能无患

    每个人每天所需要的睡眠时长是不一样的.但这跟我们的基因有关系吗?最近.科学家对果蝇的研究或许能解释这一点.果蝇的一些基因似乎与它们的睡眠时长有所联系.而这些基因也与大脑发育.学习和记忆有关.

    0

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    2017-12-20 清风拂面

    谢谢.学习了

    0

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