SCI REP:胆石症与心血管疾病相关性分析!

2017-11-09 xing.T MedSci原创

该荟萃分析表明既往有GD病史的患者发生致命和非致死性CVD事件的风险大大增加。研究人员建议对此感兴趣的调查人员对这一课题进行进一步的研究。此外,在有CVD风险的男性和女性GD患者,女性比男性的风险更高。

胆石症(GD)是一种常见的消化系统疾病,与心血管疾病(CVD)有许多共同的危险因素。心血管疾病是一个重要的公共卫生问题,占总死亡率的很大一部分。最近的一些研究表明GD和CVD之间有关联,而另一些研究则表明GD和CVD之间没有相关性。近日,Scientific reports杂志上针对这一问题发表了一篇研究文章。

在该研究中,研究人员对队列研究进行了一项荟萃分析,以评估GD和CVD之间的相关性。研究人员纳入了1980年至2017年期间发表的八项研究,其中包含了将近一百万名的参与者。

研究人员从随机效应模型中得到的与GD相关的致命性和非致死性CVD事件的相对风险(RR,95%可信区间)为1.23(95%可信区间为1.17-1.30)。女性GD患者心血管事件的随机效应模型的合并的RR值为1.24(95%可信区间为1.16-1.32)。在男性GD患者中,从随机效应模型中CVD的合并RR为1.18(95%可信区间为1.06-1.31)。

该荟萃分析表明既往有GD病史的患者发生致命和非致死性CVD事件的风险大大增加。研究人员建议对此感兴趣的调查人员对这一课题进行进一步的研究。此外,在有CVD风险的男性和女性GD患者,女性比男性的风险更高。

原始出处:


Lai lai Fan,et al. The relation between gallstone disease and cardiovascular disease.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-15430-5

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