JAMA Oncology:阳性SWOG治疗试验对美国癌患者生存的影响

2017-06-19 Yara MedSci原创

SWOG治疗试验对60岁以上癌症患者的人口存活产生了重大影响。 NCI对癌症合作组织研究计划的投资通过其产生积极的癌症治疗试验的研究项目为美国公众提供了极大的价值和利益。

重要性：近来，科学家们对癌症相关的不同研究过程的影响进行了深入的研究。半个多世纪前，国家癌症研究所（NCI）建立了一个由公共资助的癌症合作研究组织网络，本研究系统地评估了新疗法的疗效和安全性。目的：了解在美国人群中NCI赞助的阳性癌症治疗试验在多大程度上使癌症患者受益。设计，设置和参与者：本调查采用NCI赞助的网络合作研究组SWOG的研究数据。确定了SWOG 60年历史（1956 - 2016年）期间的所有治疗试验，新的实验治疗在总体生存率方面提供了统计学显著的改善。据认为，这些试验的新的成熟治疗方案为治疗社区的癌症护理建立了新的标准。从各种不同的疾病情况中确定了二十三个阳性SWOG治疗试验。主要结果和措施：本研究综合了23项治疗试验以及截止2015年的人口寿命，将新治疗对美国癌症人群的影响用Kaplan-Meier生存曲线法进行绘制，结合试验特异性危险功能和风险比对，以及监测，流行病学和最终结果计划和生命表数据。美元投资回报率为NCI在治疗试验计划中的总投资的比例除以获得的寿命年的估计。结果：从1965年到2012年，共有12361例患者参加了23项阳性试验。该研究估计，从2

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2018-03-12 tastas

#患者生存#

28 0
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2018-03-07 minlingfeng

#Oncol#

23 0
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2017-10-31 circumcision

#Oncology#

27 0
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2017-06-20 ylzr123

感谢小编为我们准备了如此丰盛的精神大餐，同时也向作者致谢！认真学习了，点赞！

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