Stroke:中性粒细胞-淋巴细胞比例增高预测脑卒中相关肺炎的价值

2018-09-10 shaosai MedSci原创

背景:尽管有很多危险指标及模型能够预测脑卒中相关肺炎(SAP),尚需更多客观和简单的预测指标。本研究评价中性粒细胞-淋巴细胞比例(NLR)与SAP在急性脑卒中患者中的相关性。

背景:尽管有很多危险指标及模型能够预测脑卒中相关肺炎(SAP),尚需更多客观和简单的预测指标。本研究评价中性粒细胞-淋巴细胞比例(NLR)与SAP在急性脑卒中患者中的相关性。

方法:本研究共纳入了1317例急性脑卒中的患者。根据改良DCP标准中定义的SAP。利用肺炎严重程度只是评分、快速SOFA和APCHE II评价肺炎严重程度。在分离中性粒细胞绝对计数和淋巴细胞绝对计数后计算NLR。

结果:共有112例患者出现肺炎(9%)。利用多便利分析,NLR在有无肺炎患者中具有显着性差异(OR=1.55; 95% CI=1.15-2.11; P=0.005)。除了年龄、房颤和脑卒中病史、NIHSS评分和C反应蛋白,NLR可作为SAP的独立预测因子当利用肺炎严重程度指数(P<0.001)、快速SOFA(P<0.001)和APCHE II(P<0.004)中,在重度肺炎患者中NLR要明显增高。另外,SAP的患者在住院期间和出院后的临床预后均较差。

本研究表明,NLR增高能够预测急性脑卒中患者发生SAP。NLR有助于及时识别高危患者,并提供有效的抗生素治疗的相关信息。

原始出处:

Ki-Woong Nam; Tae Jung Kim; Ji Sung Lee. et al.High Neutrophil-to-Lymphocyte Ratio Predicts Stroke-Associated Pneumonia.Radiology.DOI: 10.1161/STROKEAHA.118.021228

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    2018-09-12 liuxiaona
  5. [GetPortalCommentsPageByObjectIdResponse(id=1990044, encodeId=7a48199004442, content=<a href='/topic/show?id=5c0de794489' target=_blank style='color:#2F92EE;'>#细胞比例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77944, encryptionId=5c0de794489, topicName=细胞比例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ad7f282, createdName=yang0210, createdTime=Sat Oct 06 06:54:00 CST 2018, time=2018-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296681, encodeId=dcb7129668156, content=<a href='/topic/show?id=29c82219e47' target=_blank style='color:#2F92EE;'>#中性粒细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22197, encryptionId=29c82219e47, topicName=中性粒细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3883266, createdName=yykkxiaodou, createdTime=Wed Sep 12 14:54:00 CST 2018, time=2018-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1302189, encodeId=522313021891e, content=<a href='/topic/show?id=82a6659902c' target=_blank style='color:#2F92EE;'>#淋巴细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65990, encryptionId=82a6659902c, topicName=淋巴细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e34303, createdName=wetgdt, createdTime=Wed Sep 12 14:54:00 CST 2018, time=2018-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561610, encodeId=92d41561610fb, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Wed Sep 12 14:54:00 CST 2018, time=2018-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567619, encodeId=e844156e61995, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Wed Sep 12 14:54:00 CST 2018, time=2018-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026147, encodeId=f761102614e14, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Sep 11 02:54:00 CST 2018, time=2018-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344441, encodeId=fabf34444102, content=学习了很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Sep 11 00:07:07 CST 2018, time=2018-09-11, status=1, ipAttribution=)]
    2018-09-12 docwu2019
  6. [GetPortalCommentsPageByObjectIdResponse(id=1990044, encodeId=7a48199004442, content=<a href='/topic/show?id=5c0de794489' target=_blank style='color:#2F92EE;'>#细胞比例#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=77944, encryptionId=5c0de794489, topicName=细胞比例)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ad7f282, createdName=yang0210, createdTime=Sat Oct 06 06:54:00 CST 2018, time=2018-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1296681, encodeId=dcb7129668156, content=<a href='/topic/show?id=29c82219e47' target=_blank style='color:#2F92EE;'>#中性粒细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22197, encryptionId=29c82219e47, topicName=中性粒细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3883266, createdName=yykkxiaodou, createdTime=Wed Sep 12 14:54:00 CST 2018, time=2018-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1302189, encodeId=522313021891e, content=<a href='/topic/show?id=82a6659902c' target=_blank style='color:#2F92EE;'>#淋巴细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=65990, encryptionId=82a6659902c, topicName=淋巴细胞)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e34303, createdName=wetgdt, createdTime=Wed Sep 12 14:54:00 CST 2018, time=2018-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1561610, encodeId=92d41561610fb, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=af9415191444, createdName=liuxiaona, createdTime=Wed Sep 12 14:54:00 CST 2018, time=2018-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1567619, encodeId=e844156e61995, content=<a href='/topic/show?id=118142341b1' target=_blank style='color:#2F92EE;'>#增高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=42341, encryptionId=118142341b1, topicName=增高)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=docwu2019, createdTime=Wed Sep 12 14:54:00 CST 2018, time=2018-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1026147, encodeId=f761102614e14, content=卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=健健, createdTime=Tue Sep 11 02:54:00 CST 2018, time=2018-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=344441, encodeId=fabf34444102, content=学习了很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Sep 11 00:07:07 CST 2018, time=2018-09-11, status=1, ipAttribution=)]
    2018-09-11 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0

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    2018-09-11 飛歌

    学习了很不错

    0

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