STROKE:γ-谷氨酰转移酶与缺血性卒中的死亡率密切相关!

2017-09-16 MedSci MedSci原创

近期,一项发表在杂志STROKE上的研究的旨在评估入院时血清γ-谷氨酰转移酶(GGT)浓度与急性缺血性卒中患者1年全因或心血管疾病(CVD)死亡率的关系。此项前瞻性多中心队列研究在中国的4个卒中中心进行。研究者们检测了基线时GGT的水平。在为期1年的随访中检查了GGT与全因死亡或CVD死亡风险的关系。此项研究共记录了5912例中风患者的相关数据。在这些患者中,51.0%为男性,中位年龄为61岁。在

近期,一项发表在杂志STROKE上的研究的旨在评估入院时血清γ-谷氨酰转移酶(GGT)浓度与急性缺血性卒中患者1年全因或心血管疾病(CVD)死亡率的关系。

此项前瞻性多中心队列研究在中国的4个卒中中心进行。研究者们检测了基线时GGT的水平。在为期1年的随访中检查了GGT与全因死亡或CVD死亡风险的关系。

此项研究共记录了5912例中风患者的相关数据。在这些患者中,51.0%为男性,中位年龄为61岁。在男性和女性中,高GGT水平与全因死亡或CVD的总死亡率显着相关(P <0.001)。 GGT升高显示了全因死亡和CVD的死亡率的调整风险比(95%置信区间)分别为3.03(1.99-4.54)和3.24(2.14-4.92)。与其他因素相比,GGT显示出更大的区别能力来预测全因死亡率,其曲线下面积为0.69(95%置信区间,0.66-0.73)。 GGT改善了国立卫生研究院卒中量表评分(组合模型曲线下面积0.75(95%置信区间,0.73-0.78); P <0.01)。

此项研究表明,GGT与缺血性卒中患者的全因死亡率和CVD死亡率独立相关。

原始出处:
Tu WJ, Liu Q, et al. γ-Glutamyl Transferase as a Risk Factor for All-Cause or Cardiovascular Disease Mortality Among 5912 Ischemic Stroke. Stroke. 2017 Sep 13. pii: STROKEAHA.117.017776. doi: 10.1161/STROKEAHA.117.017776.

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    2017-09-16 lucycici

    学习一下

    0

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    2017-09-16 海棠胜雪

    学习了

    0

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    2017-09-16 thlabcde

    好资料学习了!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1892943, encodeId=55991892943f2, content=<a href='/topic/show?id=c738e93521f' target=_blank style='color:#2F92EE;'>#缺血性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79352, encryptionId=c738e93521f, topicName=缺血性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=66ec123, createdName=guihongzh, createdTime=Thu Aug 30 04:56:00 CST 2018, time=2018-08-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1806183, encodeId=e96d180618383, content=<a href='/topic/show?id=b649e9358fa' target=_blank style='color:#2F92EE;'>#缺血性卒#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79358, encryptionId=b649e9358fa, topicName=缺血性卒)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=636e2500187, createdName=12498da4m32(暂无昵称), createdTime=Mon Oct 30 23:56:00 CST 2017, time=2017-10-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244802, encodeId=3f912448028e, content=学习一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/syBKejEucZo9aZXqKib7wdZYRpZOzeEKDyA59Er4fkK2ff1X7w9pfDTWUY75EBCpsNo0iaGqly7sJMtEPI2Pur6Q/0, createdBy=eb672097339, createdName=lucycici, createdTime=Sat Sep 16 23:55:28 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244740, encodeId=1e7b244e4004, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuCl4zaE0zq0kFsKQmg3vef7gFticiaFX50TWZibZibNHbk3YSJ5uSh1a0DcUiaVIHkoe2Om3eYg7oUTlf/0, createdBy=442c2063958, createdName=海棠胜雪, createdTime=Sat Sep 16 22:18:33 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244710, encodeId=dee1244e1021, content=好资料学习了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=84, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Sat Sep 16 21:02:21 CST 2017, time=2017-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=244645, encodeId=aeda24464567, content=谢谢.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/Q3auHgzwzM4o2XVpJ6449yqDsjibydI5HnJ8MibGxNn4HZiaZib0bdfibbwoz3KQrIyN9AGxq36ZlZRNicYlPfOOWMtwgsajY6mGNFiaPclFdowjD0/0, createdBy=97bd1338592, createdName=清风拂面, createdTime=Sat Sep 16 13:47:53 CST 2017, time=2017-09-16, status=1, ipAttribution=)]
    2017-09-16 清风拂面

    谢谢.谢谢分享

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