Arthritis Rheum:西兰花可有效预防关节炎

2013-09-03 刘海英 中国科技网

英国东英吉利大学最新一项研究发现,萝卜硫素对于关节软骨损伤具有很好的预防和缓解作用,经常食用如西兰花等富含该种化合物的食物,或可有效预防骨关节炎。 研究人员发现,萝卜硫素能够抑制一种导致炎症的关键分子,阻断引起关节损伤的酶。实验表明,给小鼠喂食富含萝卜硫素的食物,可有效减少小鼠的软骨损伤,相比于那些没有喂食这类食物的小鼠,它们患上骨关节炎的几率明显降低。研究人员观察了萝卜硫素对人类软骨细

英国东英吉利大学最新一项研究发现,萝卜硫素对于关节软骨损伤具有很好的预防和缓解作用,经常食用如西兰花等富含该种化合物的食物,或可有效预防骨关节炎。【原文下载

研究人员发现,萝卜硫素能够抑制一种导致炎症的关键分子,阻断引起关节损伤的酶。实验表明,给小鼠喂食富含萝卜硫素的食物,可有效减少小鼠的软骨损伤,相比于那些没有喂食这类食物的小鼠,它们患上骨关节炎的几率明显降低。研究人员观察了萝卜硫素对人类软骨细胞和牛的软骨组织的影响,同样证明了这种化合物具有减缓软骨损伤的功用。

萝卜硫素是十字花科蔬菜中富含的一种化合物,如球芽甘蓝、卷心菜,都含有丰富的萝卜硫素,而西兰花则是萝卜硫素含量最丰富的一种蔬菜。过去有研究表明,这种化合物具有抗癌、消炎作用,但此次则是首次研究这种化合物对关节健康的作用。

研究人员表示,软骨细胞、软骨组织以及小鼠这三种实验模型都表明了萝卜硫素有助于软骨健康,这意味着食疗或许是一种预防和减缓骨关节炎的有效方法。无论是对于关节炎患者还是健康人士来说,经常食用西兰花等富含萝卜硫素的食物,都将是一个很好的选择。

原文下载

Davidson RK, Jupp O, de Ferrars R, Kay CD, Culley KL, Norton R, Driscoll C, Vincent TL, Donell ST, Bao Y, Clark IM.Sulforaphane represses matrix-degrading proteases and protects cartilage from destruction in vitro and in vivo.Arthritis Rheum. 2013 Aug 27    

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1972322, encodeId=c8a119e2322de, content=<a href='/topic/show?id=8a6a2e8839' target=_blank style='color:#2F92EE;'>#Arthritis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2788, encryptionId=8a6a2e8839, topicName=Arthritis)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Sat Dec 14 01:35:00 CST 2013, time=2013-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265157, encodeId=cf31126515e61, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355797, encodeId=66171355e9731, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1460712, encodeId=15281460e12bf, content=<a href='/topic/show?id=5c59904647f' target=_blank style='color:#2F92EE;'>#西兰花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90464, encryptionId=5c59904647f, topicName=西兰花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=18116361633, createdName=smallant2004, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1972322, encodeId=c8a119e2322de, content=<a href='/topic/show?id=8a6a2e8839' target=_blank style='color:#2F92EE;'>#Arthritis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2788, encryptionId=8a6a2e8839, topicName=Arthritis)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Sat Dec 14 01:35:00 CST 2013, time=2013-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265157, encodeId=cf31126515e61, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355797, encodeId=66171355e9731, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1460712, encodeId=15281460e12bf, content=<a href='/topic/show?id=5c59904647f' target=_blank style='color:#2F92EE;'>#西兰花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90464, encryptionId=5c59904647f, topicName=西兰花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=18116361633, createdName=smallant2004, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=)]
    2013-09-05 lmm397
  3. [GetPortalCommentsPageByObjectIdResponse(id=1972322, encodeId=c8a119e2322de, content=<a href='/topic/show?id=8a6a2e8839' target=_blank style='color:#2F92EE;'>#Arthritis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2788, encryptionId=8a6a2e8839, topicName=Arthritis)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Sat Dec 14 01:35:00 CST 2013, time=2013-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265157, encodeId=cf31126515e61, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355797, encodeId=66171355e9731, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1460712, encodeId=15281460e12bf, content=<a href='/topic/show?id=5c59904647f' target=_blank style='color:#2F92EE;'>#西兰花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90464, encryptionId=5c59904647f, topicName=西兰花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=18116361633, createdName=smallant2004, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=)]
    2013-09-05 zhaojie88
  4. [GetPortalCommentsPageByObjectIdResponse(id=1972322, encodeId=c8a119e2322de, content=<a href='/topic/show?id=8a6a2e8839' target=_blank style='color:#2F92EE;'>#Arthritis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2788, encryptionId=8a6a2e8839, topicName=Arthritis)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIibticIBly5jCSic5ZElW4He3rO4DMpUHUFaFX57OicNMnzckWaicBNeStwugWHFCuOdicoakApM4HGmtw/132, createdBy=f8672500006, createdName=ms6390871039024434, createdTime=Sat Dec 14 01:35:00 CST 2013, time=2013-12-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1265157, encodeId=cf31126515e61, content=<a href='/topic/show?id=57a53011364' target=_blank style='color:#2F92EE;'>#关节炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30113, encryptionId=57a53011364, topicName=关节炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1355797, encodeId=66171355e9731, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1460712, encodeId=15281460e12bf, content=<a href='/topic/show?id=5c59904647f' target=_blank style='color:#2F92EE;'>#西兰花#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=90464, encryptionId=5c59904647f, topicName=西兰花)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=18116361633, createdName=smallant2004, createdTime=Thu Sep 05 02:35:00 CST 2013, time=2013-09-05, status=1, ipAttribution=)]

相关资讯

Am J Gastroenterol:新型PROBE试验证实塞来昔布消化道副反应更低

非甾体类消炎药是一种缓解关节炎疼痛的主要用药,其最主要的副作用是损伤消化道粘膜引起消化性溃疡甚至出血。之前有前瞻性、随机、对照临床研究表明,与非选择性非甾体类消炎药相比较,高选择性非甾体类消炎药(针对COX-2)对消化道的损伤较小。然而这些研究大多都只关注该类药物对上消化道的影响。因为之前的临床实验在方案选择上十分局限,所以针对非甾体类消炎药在临床实践中的应用特点并未完全涉及,如为了减少消化道副作

OARSI:推荐膝、髋关节炎机能指标

  美国费城——国际骨关节炎研究学会(ORSI)日前推荐了一套针对明确髋、膝骨关节炎患者的易于使用的身体机能指标。   最核心的检查包括30秒连续座椅站立、40米快步走和上下楼梯。另2项检查——起立-行走计时测试和6分钟步行——也获得了强烈推荐,建议根据研究设计将其用于检测ambulatory transitions和有氧能力。   指导委员会委员Kim L. Bennell博士在世界骨关节炎

Plos One:miR-24和miR-125a-5p可能作为分子标志物诊断类风湿性关节炎

日本京都大学日前发表公报说,其研究小组开发出一种诊断类风湿性关节炎的新方法,通过检查血液中两种小核糖核酸数量的变化,能以很高的准确率确定患者是否患上了类风湿性关节炎。 小核糖核酸是一类不编码制造蛋白质的单链核糖核酸分子,主要参与控制基因表达。类风湿性关节炎是手脚等关节部位的慢性炎症,往往会导致关节和周边骨骼功能破坏和畸形。目前,日本国内约有60万类风湿性关节炎患者,但是利用以前的检查方法,约有3

FDA批准诺华旗下Ilaris用于治疗儿童关节炎

5月10日,诺华表示美国食品药品管理局(FDA)批准该公司用于治疗严重型儿童关节炎的药物Ilaris。诺华声称,Ilaris是一种全人源化单克隆抗体,能够靶向阻断白细胞介素-1β,白细胞介素-1β的过度产生在某些炎性疾病中扮演重要角色角色。Ilaris可每月皮下注射一次,是目前唯一一个被批准用来治疗该种疾病的药物。Ilaris还在欧盟被批准用于治疗难治性痛风性关节炎。与关节炎相关的拓展阅读:OAR

JBMR:弥漫性特发性骨质增生症(DISH)小鼠模型制备成功

来自加拿大西安大略大学(Western University)的科学家在关节炎研究取得了突破性进展,有望更好地了解一种最常见形式的关节炎内在机制。 根据关节炎协会( The Arthritis Society),继骨性关节炎之后,弥漫性特发性骨质增生症(DISH)是第二种最常见关节炎。该病影响着北美6~12%的人口,通常患者年龄超过50岁。DISH被定义为一种退行性关节炎,其特征是颈部及背部椎骨

Ann Rheum Dis:HIF-1α激活天然免疫反应诱发类风湿关节炎的发病

近日,北京大学人民医院风湿免疫科主任栗占国教授课题组发现了类风湿关节炎新的发病机制。课题组研究发现,低氧和低氧诱导因子(HIF)-1α可激活天然免疫反应,诱发类风湿关节炎的发生。这使人们在细胞和分子水平上对类风湿关节炎的发病机制有了新的认识。这一新的发病机制的发现可以作为生物治疗的新靶点,有望成为类风湿关节炎领域的突破口。 该研究发现,在低氧条件下,细菌、病毒等天然感染可以刺激类风湿关节炎滑膜成