SCI REP:多吃西红柿可减少皮肤癌的发展

2017-07-14 MedSci MedSci原创

俄亥俄州立大学(Ohio State University)的一项动物实验研究表明,每日摄入番茄可以降低小鼠皮肤癌肿瘤的发展。《科学报告》杂志在线刊登了一项关于营养干预如何改变皮肤癌风险的新研究。研究发现,给雄性老鼠每天喂食10%的番茄粉,持续35周,然后将其曝露在紫外线下,与不吃脱水番茄的老鼠相比,实验组的皮肤癌肿瘤平均减少了50%。番茄和癌症之间的关系的理论解释是,膳食类胡萝卜素,赋予番茄颜色


俄亥俄州立大学(Ohio State University)的一项动物实验研究表明,每日摄入番茄可以降低小鼠皮肤癌肿瘤的发展。

《科学报告》杂志在线刊登了一项关于营养干预如何改变皮肤癌风险的新研究。

研究发现,给雄性老鼠每天喂食10%的番茄粉,持续35周,然后将其曝露在紫外线下,与不吃脱水番茄的老鼠相比,实验组的皮肤癌肿瘤平均减少了50%。番茄和癌症之间的关系的理论解释是,膳食类胡萝卜素,赋予番茄颜色的化合物,可保护皮肤免受紫外线的伤害,杰西卡·库珀斯通(Jessica Cooperstone)说,她是俄亥俄州食品农业与环境科学学院食品科学与技术系研究科学家。

在研究中,雌性小鼠的肿瘤数目没有显着差异。先前的研究已经表明,雄性小鼠在紫外线照射后会发生肿瘤,并且肿瘤数量更多,更大,更具攻击性。该研究的资深作者、俄亥俄州立综合癌症中心的病理学教授Tatiana Oberyszyn说:"这项研究表明,在探索不同的预防策略时,我们确实需要考虑性别因素。"

"在男人身上有用的东西在女人身上未必有效,反之亦然。"

以前的人体临床试验表明,食用一段时间番茄酱可以抑制晒伤,也许是由于番茄中的类胡萝卜素沉积在人类皮肤中,并能防止紫外线的伤害,Cooperstone说。

她说:"番茄红素是番茄中的主要类胡萝卜素,它被证明是这些色素中最有效的抗氧化剂。" 然而,当比较整个食物(番茄)与合成补充剂中的番茄红素时,番茄在防止紫外线照射后发红方面更有效,这表明番茄中的其他化合物也可能起作用。

在这项新的研究中,俄亥俄州立大学的研究人员发现,只吃脱水红番茄的雄性老鼠,肿瘤的生长就会减少。之前的研究表明,与对照组相比,橘色番茄中番茄红素的生物利用度更高,肿瘤更少,但差异无统计学意义。

Cooperstone目前正在研究番茄红素以外的可能会给健康带来好处的化合物。

根据美国癌症协会(American Cancer Society)的报告,非黑素瘤皮肤癌是所有癌症中最常见的,2012年540万例,每年新增病例比乳腺癌,前列腺癌,肺癌结肠癌的总和还多。

根据美国卫生和人类服务部的数据,尽管死亡率很低,但这些癌症花费高昂、毁容,而且它们的发病率也在增加。

Cooperstone说:"系统保护的替代方法可能通过营养干预来调节皮肤相关疾病的风险,具有显著的益处。

她说:"食品不是药物,但在一生消费的中可能会改变某些疾病的发展。"

原文出处:Jessica L. Cooperstone et al. Tomatoes protect against development of UV-induced keratinocyte carcinoma via metabolomic alterations, Scientific Reports (2017).

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    2017-07-15 luominglian113

    学习了,谢谢分享

    0

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    2017-07-15 有备才能无患

    食品不是药物,但在一生消费的中可能会改变某些疾病的发展。"

    0

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createdBy=29392048316, createdName=王秀, createdTime=Fri Jul 14 23:35:38 CST 2017, time=2017-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222345, encodeId=2bf322234559, content=这也行!!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4PNicOvbHfgIficrsEKztlD5yv1UnCFhnFmFU9yv1RHLflMRibWrppbsiccfMB8tT9HCkAr3zL2zVml/0, createdBy=89da1604922, createdName=䖝二, createdTime=Fri Jul 14 23:33:28 CST 2017, time=2017-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222344, encodeId=54292223445a, content=学习了。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhYUE4da7HxQiaMRRk8Ix0r6sfdeeibLPNib7H5IoNf4kYsecwUsmQC1eUMKsNb65twN7epPZaicdLRCu/0, createdBy=ba1a1999418, createdName=Norene, createdTime=Fri Jul 14 23:25:25 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-15 ylzr123

    认真学习,不断进步,把经验分享给同好。点赞了!

    0

  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhYUE4da7HxQiaMRRk8Ix0r6sfdeeibLPNib7H5IoNf4kYsecwUsmQC1eUMKsNb65twN7epPZaicdLRCu/0, createdBy=ba1a1999418, createdName=Norene, createdTime=Fri Jul 14 23:25:25 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-15 传说中的大哥

    食疗,现在跟中医理论有一拼

    0

  5. 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    2017-07-15 忠诚向上

    好好看一下,继续学习

    0

  6. 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createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhYUE4da7HxQiaMRRk8Ix0r6sfdeeibLPNib7H5IoNf4kYsecwUsmQC1eUMKsNb65twN7epPZaicdLRCu/0, createdBy=ba1a1999418, createdName=Norene, createdTime=Fri Jul 14 23:25:25 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-15 189****1577

    值得推荐一下

    0

  7. 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06:30:11 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222410, encodeId=0ced2224100d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Sat Jul 15 06:29:01 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222346, encodeId=8d842223460b, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Fri Jul 14 23:35:38 CST 2017, time=2017-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222345, encodeId=2bf322234559, content=这也行!!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4PNicOvbHfgIficrsEKztlD5yv1UnCFhnFmFU9yv1RHLflMRibWrppbsiccfMB8tT9HCkAr3zL2zVml/0, createdBy=89da1604922, createdName=䖝二, createdTime=Fri Jul 14 23:33:28 CST 2017, time=2017-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222344, encodeId=54292223445a, content=学习了。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhYUE4da7HxQiaMRRk8Ix0r6sfdeeibLPNib7H5IoNf4kYsecwUsmQC1eUMKsNb65twN7epPZaicdLRCu/0, createdBy=ba1a1999418, createdName=Norene, createdTime=Fri Jul 14 23:25:25 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-15 刘煜

    学习了谢谢分享

    0

  8. 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createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhYUE4da7HxQiaMRRk8Ix0r6sfdeeibLPNib7H5IoNf4kYsecwUsmQC1eUMKsNb65twN7epPZaicdLRCu/0, createdBy=ba1a1999418, createdName=Norene, createdTime=Fri Jul 14 23:25:25 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-14 王秀

    学习了,涨知识了!

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhYUE4da7HxQiaMRRk8Ix0r6sfdeeibLPNib7H5IoNf4kYsecwUsmQC1eUMKsNb65twN7epPZaicdLRCu/0, createdBy=ba1a1999418, createdName=Norene, createdTime=Fri Jul 14 23:25:25 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-14 䖝二

    这也行!!!!

    0

  10. 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06:30:11 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222410, encodeId=0ced2224100d, content=学习了谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Sat Jul 15 06:29:01 CST 2017, time=2017-07-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222346, encodeId=8d842223460b, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Fri Jul 14 23:35:38 CST 2017, time=2017-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222345, encodeId=2bf322234559, content=这也行!!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K4PNicOvbHfgIficrsEKztlD5yv1UnCFhnFmFU9yv1RHLflMRibWrppbsiccfMB8tT9HCkAr3zL2zVml/0, createdBy=89da1604922, createdName=䖝二, createdTime=Fri Jul 14 23:33:28 CST 2017, time=2017-07-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=222344, encodeId=54292223445a, content=学习了。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhYUE4da7HxQiaMRRk8Ix0r6sfdeeibLPNib7H5IoNf4kYsecwUsmQC1eUMKsNb65twN7epPZaicdLRCu/0, createdBy=ba1a1999418, createdName=Norene, createdTime=Fri Jul 14 23:25:25 CST 2017, time=2017-07-14, status=1, ipAttribution=)]
    2017-07-14 Norene

    学习了。。。。

    0

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