NEJM:环状龟头炎-案例报道

2017-01-12 xing.T MedSci原创

该患者口服单一剂量的阿奇霉素1g,并且开始抗病毒治疗。接下来的一个月中,该环状龟头炎仍然存在。给予0.1%他克莫司外用,病人的这一症状10天后完全缓解。

患者为37岁的男性,7天前因生殖器出现病变而就诊。该患者同时伴有体重减轻(约4公斤)、疲劳、背部疼痛,但无胃肠道症状。在就诊前两个月,患者出现过排尿困难和尿道分泌物等症状,并且这些症状自行消失。患者没有定期服用过任何药物,也无明确的就诊史。



 
体检发现患者龟头部位有红色、边界清楚的环形斑块,并且伴有尿道口炎症(如图A和B所示),患者双眼均伴有结膜感染。病原学检查发现该患者人类免疫缺陷病毒(HIV)检测结果阳性,并且病毒载量为15000拷贝数/mL。CD4阳性T细胞计数为172个/mL。类风湿因子检测结果为阴性,但HLA-B27为阳性。收集患者的血清标本,检测乙型肝炎病毒、丙型肝炎病毒和梅毒结果均为阴性。在尿道拭子标本中通过核酸扩增检测了沙眼衣原体感染。
 
该患者口服单一剂量的阿奇霉素1g,并且开始抗病毒治疗。接下来的一个月中,该环状龟头炎仍然存在。给予0.1%他克莫司外用,病人的这一症状10天后完全缓解。
 
原始出处:
 
Ana Pulido-Perez, et al. Circinate Balanitis. N Engl J Med .January 12, 2017. 

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1822584, encodeId=a8dd18225849f, content=<a href='/topic/show?id=aeef10360392' target=_blank style='color:#2F92EE;'>#龟头炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103603, encryptionId=aeef10360392, topicName=龟头炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Wed Oct 18 16:01:00 CST 2017, time=2017-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172016, encodeId=fced1e201667, content=艾滋病毒引起的?, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2dd71722896, createdName=studylzc, createdTime=Sun Jan 22 19:22:46 CST 2017, time=2017-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170170, encodeId=88011e0170bb, content=学习了!有意思的病例!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Fri Jan 13 23:38:13 CST 2017, time=2017-01-13, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1822584, encodeId=a8dd18225849f, content=<a href='/topic/show?id=aeef10360392' target=_blank style='color:#2F92EE;'>#龟头炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103603, encryptionId=aeef10360392, topicName=龟头炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Wed Oct 18 16:01:00 CST 2017, time=2017-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172016, encodeId=fced1e201667, content=艾滋病毒引起的?, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2dd71722896, createdName=studylzc, createdTime=Sun Jan 22 19:22:46 CST 2017, time=2017-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170170, encodeId=88011e0170bb, content=学习了!有意思的病例!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Fri Jan 13 23:38:13 CST 2017, time=2017-01-13, status=1, ipAttribution=)]
    2017-01-22 studylzc

    艾滋病毒引起的?

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1822584, encodeId=a8dd18225849f, content=<a href='/topic/show?id=aeef10360392' target=_blank style='color:#2F92EE;'>#龟头炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103603, encryptionId=aeef10360392, topicName=龟头炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=930e243, createdName=dingxiaobo, createdTime=Wed Oct 18 16:01:00 CST 2017, time=2017-10-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172016, encodeId=fced1e201667, content=艾滋病毒引起的?, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=2dd71722896, createdName=studylzc, createdTime=Sun Jan 22 19:22:46 CST 2017, time=2017-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=170170, encodeId=88011e0170bb, content=学习了!有意思的病例!, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLC1BMzZWdMSPQWuib6BtQGicK8ygGBM6YakpfkRc67soFSuKbZr86enL1KggQZEZbgWSeicJibafmYfQ3AibicIHMwwicmDShfRFvvI38/0, createdBy=272a110164, createdName=laoli, createdTime=Fri Jan 13 23:38:13 CST 2017, time=2017-01-13, status=1, ipAttribution=)]
    2017-01-13 laoli

    学习了!有意思的病例!

    0